SYNDAX PHARMACEUTICALS INC

Ticker: SNDX CUSIP: 87164F105 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 632,752 Value ($000) $13,294 Avg Close $17.45 Range $12.99 - $22.73

Q3 2025

Shares 383,052 Value ($000) $5,893 Avg Close $13.09 Range $8.59 - $17.24

Q2 2025

Shares 392,452 Value ($000) $3,675 Avg Close $11.01 Range $8.58 - $14.24

Q1 2025

Shares 503,152 Value ($000) $6,181 Avg Close $14.10 Range $12.06 - $16.95

Q4 2024

Shares 535,952 Value ($000) $7,085 Avg Close $17.11 Range $12.40 - $22.50

Q3 2024

Shares 669,352 Value ($000) $12,885 Avg Close $20.66 Range $17.34 - $25.07

Q2 2024

Shares 621,252 Value ($000) $12,754 Avg Close $20.93 Range $18.65 - $24.38

Q1 2024

Shares 455,852 Value ($000) $10,849 Avg Close $22.30 Range $19.58 - $25.34

Q4 2023

Shares 151,452 Value ($000) $3,273 Avg Close $15.37 Range $11.21 - $21.84

Q3 2023

Shares 67,052 Value ($000) $974 Avg Close $18.92 Range $12.85 - $23.55

Q2 2023

Shares 137,152 Value ($000) $2,871 Avg Close $20.82 Range $19.27 - $23.14

Q1 2023

Shares 263,352 Value ($000) $5,562 Avg Close $24.88 Range $20.01 - $29.86

Q4 2022

Shares 317,852 Value ($000) $8,089 Avg Close $23.32 Range $20.25 - $26.51

Q3 2022

Shares 371,752 Value ($000) $8,933 Avg Close $22.44 Range $18.05 - $25.71

Q2 2022

Shares 352,852 Value ($000) $6,789 Avg Close $16.66 Range $13.27 - $19.91

Q1 2022

Shares 368,352 Value ($000) $6,402 Avg Close $16.84 Range $14.56 - $22.27

Q4 2021

Shares 354,552 Value ($000) $7,761 Avg Close $18.48 Range $14.76 - $22.71

Q3 2021

Shares 341,852 Value ($000) $6,533 Avg Close $16.66 Range $13.58 - $20.32

Q2 2021

Shares 428,452 Value ($000) $7,357 Avg Close $18.32 Range $13.02 - $25.46

Q1 2021

Shares 581,752 Value ($000) $13,008 Avg Close $22.59 Range $19.05 - $25.68

Q4 2020

Shares 667,552 Value ($000) $14,846 Avg Close $20.74 Range $13.92 - $27.85

Q3 2020

Shares 259,052 Value ($000) $3,824 Avg Close $15.24 Range $13.04 - $17.99

Q2 2020

Shares 200,552 Value ($000) $2,972 Avg Close $15.23 Range $8.72 - $21.97

Q1 2020

Shares 51,552 Value ($000) $566 Avg Close $9.38 Range $6.32 - $12.27

Q4 2019

Shares 34,452 Value ($000) $302 Avg Close $7.34 Range $5.35 - $9.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	632,752	$13,294	$17.45	$12.99 - $22.73
Q3 2025	383,052	$5,893	$13.09	$8.59 - $17.24
Q2 2025	392,452	$3,675	$11.01	$8.58 - $14.24
Q1 2025	503,152	$6,181	$14.10	$12.06 - $16.95
Q4 2024	535,952	$7,085	$17.11	$12.40 - $22.50
Q3 2024	669,352	$12,885	$20.66	$17.34 - $25.07
Q2 2024	621,252	$12,754	$20.93	$18.65 - $24.38
Q1 2024	455,852	$10,849	$22.30	$19.58 - $25.34
Q4 2023	151,452	$3,273	$15.37	$11.21 - $21.84
Q3 2023	67,052	$974	$18.92	$12.85 - $23.55
Q2 2023	137,152	$2,871	$20.82	$19.27 - $23.14
Q1 2023	263,352	$5,562	$24.88	$20.01 - $29.86
Q4 2022	317,852	$8,089	$23.32	$20.25 - $26.51
Q3 2022	371,752	$8,933	$22.44	$18.05 - $25.71
Q2 2022	352,852	$6,789	$16.66	$13.27 - $19.91
Q1 2022	368,352	$6,402	$16.84	$14.56 - $22.27
Q4 2021	354,552	$7,761	$18.48	$14.76 - $22.71
Q3 2021	341,852	$6,533	$16.66	$13.58 - $20.32
Q2 2021	428,452	$7,357	$18.32	$13.02 - $25.46
Q1 2021	581,752	$13,008	$22.59	$19.05 - $25.68
Q4 2020	667,552	$14,846	$20.74	$13.92 - $27.85
Q3 2020	259,052	$3,824	$15.24	$13.04 - $17.99
Q2 2020	200,552	$2,972	$15.23	$8.72 - $21.97
Q1 2020	51,552	$566	$9.38	$6.32 - $12.27
Q4 2019	34,452	$302	$7.34	$5.35 - $9.47