TECTONIC THERAPEUTIC INC

Ticker: TECX CUSIP: 878972108 Class: Common Stock

5AM Venture Management, LLC's Holding History (CIK: 0001799883)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 606,660 Value ($000) $12,655 Avg Close $18.58 Range $14.60 - $26.00

Q3 2025

Shares 511,660 Value ($000) $8,028 Avg Close $20.64 Range $14.39 - $27.33

Q2 2025

Shares 511,660 Value ($000) $10,167 Avg Close $20.27 Range $13.70 - $25.75

Q1 2025

Shares 511,660 Value ($000) $9,061 Avg Close $32.59 Range $15.30 - $61.07

Q4 2024

Shares 596,660 Value ($000) $27,548 Avg Close $42.29 Range $27.21 - $53.41

Q3 2024

Shares 646,524 Value ($000) $19,590 Avg Close $18.28 Range $15.08 - $31.66

Q2 2024

Shares 646,524 Value ($000) $10,648 Avg Close $15.77 Range $1.40 - $18.48

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	606,660	$12,655	$18.58	$14.60 - $26.00
Q3 2025	511,660	$8,028	$20.64	$14.39 - $27.33
Q2 2025	511,660	$10,167	$20.27	$13.70 - $25.75
Q1 2025	511,660	$9,061	$32.59	$15.30 - $61.07
Q4 2024	596,660	$27,548	$42.29	$27.21 - $53.41
Q3 2024	646,524	$19,590	$18.28	$15.08 - $31.66
Q2 2024	646,524	$10,648	$15.77	$1.40 - $18.48