TENAX THERAPEUTICS INC

CUSIP: 88032L100 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 390,000 Value ($000) $905 Avg Close — Range —
Q2 2016
Shares 465,000 Value ($000) $1,190 Avg Close — Range —
Q1 2016
Shares 499,600 Value ($000) $1,024 Avg Close — Range —
Q4 2015
Shares 540,000 Value ($000) $1,771 Avg Close — Range —
Q3 2015
Shares 635,000 Value ($000) $1,905 Avg Close — Range —
Q2 2015
Shares 635,000 Value ($000) $2,343 Avg Close — Range —
Q1 2015
Shares 606,200 Value ($000) $1,976 Avg Close — Range —
Q4 2014
Shares 440,000 Value ($000) $1,690 Avg Close — Range —