TESARO INC

CUSIP: 881569107 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 106,175 Value ($000) $6,067 Avg Close — Range —
Q4 2017
Shares 95,000 Value ($000) $7,873 Avg Close — Range —
Q3 2017
Shares 80,000 Value ($000) $10,328 Avg Close — Range —
Q2 2017
Shares 55,000 Value ($000) $7,692 Avg Close — Range —
Q4 2016
Shares 20,000 Value ($000) $2,690 Avg Close — Range —
Q3 2016
Shares 50,000 Value ($000) $5,012 Avg Close — Range —
Q4 2015
Shares 30,686 Value ($000) $1,605 Avg Close — Range —
Q3 2015
Shares 117,500 Value ($000) $4,712 Avg Close — Range —
Q2 2015
Shares 87,500 Value ($000) $5,144 Avg Close — Range —