TETRAPHASE PHARMACEUTICALS I

CUSIP: 88165N105 Class: COMMON STOCK

Novo Holdings A/S's Holding History (CIK: 0001388325)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 231,419 Value ($000) $8,479 Avg Close — Range —
Q4 2014
Shares 1,475,000 Value ($000) $58,572 Avg Close — Range —
Q3 2014
Shares 900,000 Value ($000) $17,955 Avg Close — Range —
Q2 2014
Shares 900,000 Value ($000) $12,141 Avg Close — Range —
Q1 2014
Shares 900,000 Value ($000) $9,801 Avg Close — Range —
Q4 2013
Shares 1,200,000 Value ($000) $16,224 Avg Close — Range —