TOBIRA THERAPEUTICS INC

CUSIP: 88883P101 Class: COMMON

Novo Holdings A/S's Holding History (CIK: 0001388325)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 2,027,091 Value ($000) $25,460 Avg Close — Range —
Q1 2016
Shares 2,281,405 Value ($000) $18,662 Avg Close — Range —
Q4 2015
Shares 2,471,405 Value ($000) $24,838 Avg Close — Range —
Q3 2015
Shares 2,696,405 Value ($000) $26,047 Avg Close — Range —
Q2 2015
Shares 2,696,405 Value ($000) $46,513 Avg Close — Range —