TRILLIUM THERAPEUTICS INC

CUSIP: 89620X506 Class: COM NEW

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 110,000 Value ($000) $622 Avg Close — Range —
Q3 2016
Shares 175,000 Value ($000) $2,587 Avg Close — Range —
Q2 2016
Shares 195,000 Value ($000) $1,751 Avg Close — Range —
Q1 2016
Shares 195,000 Value ($000) $1,804 Avg Close — Range —
Q4 2015
Shares 210,000 Value ($000) $2,648 Avg Close — Range —
Q3 2015
Shares 245,275 Value ($000) $3,196 Avg Close — Range —
Q2 2015
Shares 250,000 Value ($000) $5,455 Avg Close — Range —
Q1 2015
Shares 260,000 Value ($000) $5,260 Avg Close — Range —
Q4 2014
Shares 333,333 Value ($000) $3,000 Avg Close — Range —