TYRA BIOSCIENCES INC

Ticker: TYRA CUSIP: 90240B106 Class: Common Stock

Caligan Partners LP's Holding History (CIK: 0001727492)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 944,257 Value ($000) $24,825 Avg Close $18.37 Range $12.98 - $26.41

Q3 2025

Shares 696,825 Value ($000) $9,749 Avg Close $11.40 Range $9.10 - $14.02

Q2 2025

Shares 189,950 Value ($000) $1,818 Avg Close $9.50 Range $6.42 - $12.00

Q1 2025

Shares 25,000 Value ($000) $233 Avg Close $12.94 Range $9.04 - $17.27

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	944,257	$24,825	$18.37	$12.98 - $26.41
Q3 2025	696,825	$9,749	$11.40	$9.10 - $14.02
Q2 2025	189,950	$1,818	$9.50	$6.42 - $12.00
Q1 2025	25,000	$233	$12.94	$9.04 - $17.27