ULTRAGENYX PHARMACEUTICAL IN

Ticker: RARE CUSIP: 90400D108 Class: EQTY

Polar Capital Holdings Plc's Holding History (CIK: 0001837309)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 556,628 Value ($000) $12,802 Avg Close $32.88 Range $18.41 - $39.89

Q3 2025

Shares 583,710 Value ($000) $17,558 Avg Close $29.99 Range $25.81 - $42.37

Q2 2025

Shares 551,383 Value ($000) $20,048 Avg Close $36.05 Range $29.59 - $40.19

Q1 2025

Shares 651,383 Value ($000) $23,587 Avg Close $41.60 Range $35.53 - $46.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	556,628	$12,802	$32.88	$18.41 - $39.89
Q3 2025	583,710	$17,558	$29.99	$25.81 - $42.37
Q2 2025	551,383	$20,048	$36.05	$29.59 - $40.19
Q1 2025	651,383	$23,587	$41.60	$35.53 - $46.50