UNITED THERAPEUTICS CORP DEL

Ticker: UTHR CUSIP: 91307C102 Class: EQTY

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 1,600 Value ($000) $671 Avg Close $336.31 Range $272.12 - $442.01

Q2 2025

Shares 6,300 Value ($000) $1,810 Avg Close $298.86 Range $266.98 - $335.00

Q1 2025

Shares 9,200 Value ($000) $2,836 Avg Close $342.70 Range $298.60 - $383.51

Q4 2024

Shares 11,800 Value ($000) $4,164 Avg Close $367.56 Range $342.02 - $417.82

Q3 2024

Shares 13,101 Value ($000) $4,695 Avg Close $337.80 Range $309.04 - $366.08

Q2 2024

Shares 14,201 Value ($000) $4,524 Avg Close $264.67 Range $221.53 - $321.80

Q1 2024

Shares 113,401 Value ($000) $26,050 Avg Close $225.66 Range $208.62 - $250.89

Q4 2023

Shares 16,601 Value ($000) $3,650 Avg Close $230.49 Range $210.00 - $258.31

Q3 2023

Shares 15,101 Value ($000) $3,411 Avg Close $230.33 Range $211.25 - $261.54

Q2 2023

Shares 21,801 Value ($000) $4,813 Avg Close $221.50 Range $204.44 - $233.83

Q1 2023

Shares 73,201 Value ($000) $16,394 Avg Close $246.53 Range $211.58 - $279.14

Q4 2022

Shares 91,901 Value ($000) $25,557 Avg Close $252.44 Range $205.35 - $283.09

Q3 2022

Shares 45,101 Value ($000) $9,443 Avg Close $223.56 Range $201.65 - $245.48

Q2 2022

Shares 44,201 Value ($000) $10,416 Avg Close $203.30 Range $173.22 - $243.30

Q1 2022

Shares 17,000 Value ($000) $3,050 Avg Close $190.51 Range $158.38 - $217.84

Q4 2021

Shares 179,701 Value ($000) $38,830 Avg Close $196.31 Range $178.41 - $218.38

Q3 2021

Shares 237,101 Value ($000) $43,764 Avg Close $196.97 Range $177.82 - $216.90

Q2 2021

Shares 22,401 Value ($000) $4,019 Avg Close $190.45 Range $170.06 - $212.62

Q1 2021

Shares 33,202 Value ($000) $5,554 Avg Close $166.73 Range $150.73 - $181.14

Q3 2020

Shares 244,602 Value ($000) $24,705 Avg Close $109.72 Range $98.37 - $122.53

Q2 2020

Shares 379,603 Value ($000) $45,932 Avg Close $112.52 Range $89.89 - $127.79

Q1 2020

Shares 378,103 Value ($000) $35,854 Avg Close $95.05 Range $75.58 - $116.98

Q4 2019

Shares 402,003 Value ($000) $35,408 Avg Close $87.99 Range $76.33 - $95.90

Q3 2019

Shares 495,903 Value ($000) $39,548 Avg Close $80.53 Range $74.31 - $87.85

Q2 2019

Shares 500,803 Value ($000) $39,093 Avg Close $93.51 Range $75.72 - $121.11

Q1 2019

Shares 66,073 Value ($000) $7,755 Avg Close $116.52 Range $105.88 - $128.94

Q4 2018

Shares 86,173 Value ($000) $9,384 Avg Close $115.95 Range $100.06 - $129.59

Q3 2018

Shares 88,673 Value ($000) $11,340 Avg Close $123.69 Range $110.00 - $130.00

Q2 2018

Shares 58,673 Value ($000) $6,639 Avg Close $109.92 Range $100.57 - $118.93

Q1 2018

Shares 9,473 Value ($000) $1,064 Avg Close $127.04 Range $106.30 - $152.55

Q4 2017

Shares 18,273 Value ($000) $2,703 Avg Close $127.12 Range $115.79 - $152.47

Q3 2017

Shares 2,871 Value ($000) $336 Avg Close $127.70 Range $114.54 - $139.10

Q2 2017

Shares 243,773 Value ($000) $31,625 Avg Close $124.75 Range $112.01 - $134.16

Q1 2017

Shares 214,273 Value ($000) $29,008 Avg Close $151.49 Range $132.13 - $169.89

Q4 2016

Shares 251,973 Value ($000) $36,140 Avg Close $127.68 Range $110.90 - $147.60

Q3 2016

Shares 255,373 Value ($000) $30,154 Avg Close $120.15 Range $105.33 - $130.99

Q2 2016

Shares 309,473 Value ($000) $32,779 Avg Close $111.55 Range $97.52 - $121.69

Q1 2016

Shares 254,773 Value ($000) $28,389 Avg Close $126.54 Range $107.04 - $159.96

Q4 2015

Shares 274,854 Value ($000) $43,045 Avg Close $145.57 Range $117.88 - $164.04

Q3 2015

Shares 56,639 Value ($000) $7,433 Avg Close $160.39 Range $129.48 - $181.03

Q2 2015

Shares 4,339 Value ($000) $755 Avg Close $179.89 Range $157.20 - $190.29

Q1 2015

Shares 3,239 Value ($000) $559 Avg Close $152.45 Range $124.21 - $181.61

Q4 2014

Shares 3,739 Value ($000) $484 Avg Close $128.87 Range $118.47 - $137.84

Q3 2014

Shares 8,439 Value ($000) $1,086 Avg Close $103.09 Range $86.04 - $136.93

Q2 2014

Shares 30,439 Value ($000) $2,694 Avg Close $96.17 Range $84.63 - $109.24

Q4 2013

Shares 27,939 Value ($000) $3,159 Avg Close $90.18 Range $78.14 - $116.65

Q2 2013

Shares 19,939 Value ($000) $1,313 Avg Close $64.42 Range $59.02 - $69.65

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	1,600	$671	$336.31	$272.12 - $442.01
Q2 2025	6,300	$1,810	$298.86	$266.98 - $335.00
Q1 2025	9,200	$2,836	$342.70	$298.60 - $383.51
Q4 2024	11,800	$4,164	$367.56	$342.02 - $417.82
Q3 2024	13,101	$4,695	$337.80	$309.04 - $366.08
Q2 2024	14,201	$4,524	$264.67	$221.53 - $321.80
Q1 2024	113,401	$26,050	$225.66	$208.62 - $250.89
Q4 2023	16,601	$3,650	$230.49	$210.00 - $258.31
Q3 2023	15,101	$3,411	$230.33	$211.25 - $261.54
Q2 2023	21,801	$4,813	$221.50	$204.44 - $233.83
Q1 2023	73,201	$16,394	$246.53	$211.58 - $279.14
Q4 2022	91,901	$25,557	$252.44	$205.35 - $283.09
Q3 2022	45,101	$9,443	$223.56	$201.65 - $245.48
Q2 2022	44,201	$10,416	$203.30	$173.22 - $243.30
Q1 2022	17,000	$3,050	$190.51	$158.38 - $217.84
Q4 2021	179,701	$38,830	$196.31	$178.41 - $218.38
Q3 2021	237,101	$43,764	$196.97	$177.82 - $216.90
Q2 2021	22,401	$4,019	$190.45	$170.06 - $212.62
Q1 2021	33,202	$5,554	$166.73	$150.73 - $181.14
Q3 2020	244,602	$24,705	$109.72	$98.37 - $122.53
Q2 2020	379,603	$45,932	$112.52	$89.89 - $127.79
Q1 2020	378,103	$35,854	$95.05	$75.58 - $116.98
Q4 2019	402,003	$35,408	$87.99	$76.33 - $95.90
Q3 2019	495,903	$39,548	$80.53	$74.31 - $87.85
Q2 2019	500,803	$39,093	$93.51	$75.72 - $121.11
Q1 2019	66,073	$7,755	$116.52	$105.88 - $128.94
Q4 2018	86,173	$9,384	$115.95	$100.06 - $129.59
Q3 2018	88,673	$11,340	$123.69	$110.00 - $130.00
Q2 2018	58,673	$6,639	$109.92	$100.57 - $118.93
Q1 2018	9,473	$1,064	$127.04	$106.30 - $152.55
Q4 2017	18,273	$2,703	$127.12	$115.79 - $152.47
Q3 2017	2,871	$336	$127.70	$114.54 - $139.10
Q2 2017	243,773	$31,625	$124.75	$112.01 - $134.16
Q1 2017	214,273	$29,008	$151.49	$132.13 - $169.89
Q4 2016	251,973	$36,140	$127.68	$110.90 - $147.60
Q3 2016	255,373	$30,154	$120.15	$105.33 - $130.99
Q2 2016	309,473	$32,779	$111.55	$97.52 - $121.69
Q1 2016	254,773	$28,389	$126.54	$107.04 - $159.96
Q4 2015	274,854	$43,045	$145.57	$117.88 - $164.04
Q3 2015	56,639	$7,433	$160.39	$129.48 - $181.03
Q2 2015	4,339	$755	$179.89	$157.20 - $190.29
Q1 2015	3,239	$559	$152.45	$124.21 - $181.61
Q4 2014	3,739	$484	$128.87	$118.47 - $137.84
Q3 2014	8,439	$1,086	$103.09	$86.04 - $136.93
Q2 2014	30,439	$2,694	$96.17	$84.63 - $109.24
Q4 2013	27,939	$3,159	$90.18	$78.14 - $116.65
Q2 2013	19,939	$1,313	$64.42	$59.02 - $69.65