UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

WELLS FARGO & COMPANY/MN's Holding History (CIK: 0000072971)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 36,794 Value ($000) $999 Avg Close $24.89 Range $18.05 - $33.00

Q3 2025

Shares 25,160 Value ($000) $473 Avg Close $15.54 Range $10.54 - $21.03

Q2 2025

Shares 22,364 Value ($000) $246 Avg Close $9.24 Range $5.14 - $12.10

Q1 2025

Shares 9,250 Value ($000) $57 Avg Close $9.55 Range $6.12 - $18.95

Q4 2024

Shares 9,047 Value ($000) $149 Avg Close $22.33 Range $14.97 - $29.46

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	36,794	$999	$24.89	$18.05 - $33.00
Q3 2025	25,160	$473	$15.54	$10.54 - $21.03
Q2 2025	22,364	$246	$9.24	$5.14 - $12.10
Q1 2025	9,250	$57	$9.55	$6.12 - $18.95
Q4 2024	9,047	$149	$22.33	$14.97 - $29.46