UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

NOMURA HOLDINGS INC's Holding History (CIK: 0001163653)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 28,290 Value ($000) $532 Avg Close $15.54 Range $10.54 - $21.03

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	28,290	$532	$15.54	$10.54 - $21.03