UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

BNP PARIBAS ARBITRAGE, SA's Holding History (CIK: 0001166588)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,976 Value ($000) $135 Avg Close $24.89 Range $18.05 - $33.00

Q3 2025

Shares 6,527 Value ($000) $123 Avg Close $15.54 Range $10.54 - $21.03

Q2 2025

Shares 3,097 Value ($000) $34 Avg Close $9.24 Range $5.14 - $12.10

Q1 2025

Shares 939 Value ($000) $6 Avg Close $9.55 Range $6.12 - $18.95

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,976	$135	$24.89	$18.05 - $33.00
Q3 2025	6,527	$123	$15.54	$10.54 - $21.03
Q2 2025	3,097	$34	$9.24	$5.14 - $12.10
Q1 2025	939	$6	$9.55	$6.12 - $18.95