UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

ALPS ADVISORS INC's Holding History (CIK: 0001376113)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 44,376 Value ($000) $1,205 Avg Close $24.89 Range $18.05 - $33.00

Q3 2025

Shares 25,962 Value ($000) $488 Avg Close $15.54 Range $10.54 - $21.03

Q2 2025

Shares 28,976 Value ($000) $318 Avg Close $9.24 Range $5.14 - $12.10

Q1 2025

Shares 39,079 Value ($000) $239 Avg Close $9.55 Range $6.12 - $18.95

Q4 2024

Shares 43,340 Value ($000) $713 Avg Close $22.33 Range $14.97 - $29.46

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	44,376	$1,205	$24.89	$18.05 - $33.00
Q3 2025	25,962	$488	$15.54	$10.54 - $21.03
Q2 2025	28,976	$318	$9.24	$5.14 - $12.10
Q1 2025	39,079	$239	$9.55	$6.12 - $18.95
Q4 2024	43,340	$713	$22.33	$14.97 - $29.46