UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2024

Shares 45,549 Value ($000) $749 Avg Close $22.33 Range $14.97 - $29.46

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2024	45,549	$749	$22.33	$14.97 - $29.46