UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

Caitong International Asset Management Co., Ltd's Holding History (CIK: 0001963355)

Note: Option positions (PUT/CALL) are excluded.

Q2 2025

Shares 224 Value ($000) $2 Avg Close $9.24 Range $5.14 - $12.10

Q4 2024

Shares 44 Value ($000) $1 Avg Close $22.33 Range $14.97 - $29.46

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2025	224	$2	$9.24	$5.14 - $12.10
Q4 2024	44	$1	$22.33	$14.97 - $29.46