UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

Aster Capital Management (DIFC) Ltd's Holding History (CIK: 0002040915)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 271 Value ($000) $7 Avg Close $24.89 Range $18.05 - $33.00

Q3 2025

Shares 1,141 Value ($000) $21 Avg Close $15.54 Range $10.54 - $21.03

Q4 2024

Shares 134 Value ($000) $2 Avg Close $22.33 Range $14.97 - $29.46

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	271	$7	$24.89	$18.05 - $33.00
Q3 2025	1,141	$21	$15.54	$10.54 - $21.03
Q4 2024	134	$2	$22.33	$14.97 - $29.46