VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Associated Banc-Corp's Holding History (CIK: 0000007789)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6,947 Value ($000) $3,149 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 7,118 Value ($000) $2,788 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 7,583 Value ($000) $3,376 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 8,163 Value ($000) $3,958 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 8,828 Value ($000) $3,555 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 9,119 Value ($000) $4,241 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 9,481 Value ($000) $4,444 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 9,624 Value ($000) $4,023 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 9,755 Value ($000) $3,969 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 9,854 Value ($000) $3,427 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 9,902 Value ($000) $3,485 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 9,897 Value ($000) $3,118 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 10,704 Value ($000) $3,091 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 10,906 Value ($000) $3,158 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 11,027 Value ($000) $3,108 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 11,475 Value ($000) $2,995 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 20,597 Value ($000) $4,523 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 26,077 Value ($000) $4,730 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 30,059 Value ($000) $6,061 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 7,834 Value ($000) $1,864 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 73,531 Value ($000) $17,378 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 41,114 Value ($000) $11,188 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 17,434 Value ($000) $5,061 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 7,839 Value ($000) $1,865 Avg Close $229.39 Range $197.47 - $249.85

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6,947	$3,149	$431.03	$392.50 - $464.44
Q3 2025	7,118	$2,788	$417.92	$362.50 - $484.56
Q2 2025	7,583	$3,376	$460.83	$416.60 - $510.77
Q1 2025	8,163	$3,958	$466.00	$397.25 - $519.68
Q4 2024	8,828	$3,555	$463.53	$377.85 - $519.88
Q3 2024	9,119	$4,241	$480.37	$456.07 - $510.64
Q2 2024	9,481	$4,444	$434.05	$391.01 - $486.43
Q1 2024	9,624	$4,023	$422.74	$403.43 - $448.40
Q4 2023	9,755	$3,969	$369.42	$341.85 - $413.00
Q3 2023	9,854	$3,427	$349.73	$335.82 - $367.00
Q2 2023	9,902	$3,485	$336.94	$313.47 - $354.94
Q1 2023	9,897	$3,118	$299.93	$282.21 - $325.19
Q4 2022	10,704	$3,091	$304.77	$283.58 - $324.75
Q3 2022	10,906	$3,158	$287.72	$271.61 - $305.95
Q2 2022	11,027	$3,108	$267.66	$233.01 - $293.17
Q1 2022	11,475	$2,995	$237.33	$214.66 - $263.58
Q4 2021	20,597	$4,523	$194.45	$176.36 - $224.49
Q3 2021	26,077	$4,730	$195.24	$180.02 - $204.88
Q2 2021	30,059	$6,061	$209.17	$185.33 - $222.78
Q1 2021	7,834	$1,864	$219.65	$204.62 - $242.99
Q4 2020	73,531	$17,378	$229.44	$202.57 - $280.99
Q3 2020	41,114	$11,188	$275.88	$253.97 - $306.08
Q2 2020	17,434	$5,061	$271.12	$222.39 - $299.21
Q1 2020	7,839	$1,865	$229.39	$197.47 - $249.85