VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

BANK OF NOVA SCOTIA's Holding History (CIK: 0000009631)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 97,920 Value ($000) $44,393 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 86,252 Value ($000) $33,780 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 49,609 Value ($000) $22,086 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 27,688 Value ($000) $13,423 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 47,097 Value ($000) $18,967 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 74,670 Value ($000) $34,729 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 51,367 Value ($000) $24,070 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 225,936 Value ($000) $94,422 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 62,347 Value ($000) $25,357 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 58,963 Value ($000) $20,501 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 25,021 Value ($000) $8,805 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 23,351 Value ($000) $7,357 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 42,668 Value ($000) $12,323 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 33,726 Value ($000) $9,764 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 65,028 Value ($000) $18,327 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 43,478 Value ($000) $11,347 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 101,259 Value ($000) $22,237 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 488,459 Value ($000) $88,590 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 40,922 Value ($000) $8,251 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 50,564 Value ($000) $10,866 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 120,041 Value ($000) $28,370 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 93,697 Value ($000) $25,496 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 416,590 Value ($000) $120,940 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 362,964 Value ($000) $86,373 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 60,647 Value ($000) $13,279 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 57,062 Value ($000) $9,668 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 48,088 Value ($000) $8,818 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 48,737 Value ($000) $8,965 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 68,752 Value ($000) $11,393 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 51,944 Value ($000) $10,012 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 27,967 Value ($000) $4,753 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 32,314 Value ($000) $5,262 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 39,709 Value ($000) $5,951 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 43,760 Value ($000) $6,653 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 116,259 Value ($000) $14,982 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 56,862 Value ($000) $6,218 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 5,505 Value ($000) $406 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 5,015 Value ($000) $437 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 4,915 Value ($000) $423 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 4,595 Value ($000) $365 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 4,535 Value ($000) $571 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 4,525 Value ($000) $471 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 4,325 Value ($000) $534 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 4,197 Value ($000) $495 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 4,057 Value ($000) $482 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 4,057 Value ($000) $456 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 3,764 Value ($000) $356 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 3,355 Value ($000) $237 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 3,247 Value ($000) $241 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 3,181 Value ($000) $241 Avg Close $79.58 Range $73.43 - $89.96

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	97,920	$44,393	$431.03	$392.50 - $464.44
Q3 2025	86,252	$33,780	$417.92	$362.50 - $484.56
Q2 2025	49,609	$22,086	$460.83	$416.60 - $510.77
Q1 2025	27,688	$13,423	$466.00	$397.25 - $519.68
Q4 2024	47,097	$18,967	$463.53	$377.85 - $519.88
Q3 2024	74,670	$34,729	$480.37	$456.07 - $510.64
Q2 2024	51,367	$24,070	$434.05	$391.01 - $486.43
Q1 2024	225,936	$94,422	$422.74	$403.43 - $448.40
Q4 2023	62,347	$25,357	$369.42	$341.85 - $413.00
Q3 2023	58,963	$20,501	$349.73	$335.82 - $367.00
Q2 2023	25,021	$8,805	$336.94	$313.47 - $354.94
Q1 2023	23,351	$7,357	$299.93	$282.21 - $325.19
Q4 2022	42,668	$12,323	$304.77	$283.58 - $324.75
Q3 2022	33,726	$9,764	$287.72	$271.61 - $305.95
Q2 2022	65,028	$18,327	$267.66	$233.01 - $293.17
Q1 2022	43,478	$11,347	$237.33	$214.66 - $263.58
Q4 2021	101,259	$22,237	$194.45	$176.36 - $224.49
Q3 2021	488,459	$88,590	$195.24	$180.02 - $204.88
Q2 2021	40,922	$8,251	$209.17	$185.33 - $222.78
Q1 2021	50,564	$10,866	$219.65	$204.62 - $242.99
Q4 2020	120,041	$28,370	$229.44	$202.57 - $280.99
Q3 2020	93,697	$25,496	$275.88	$253.97 - $306.08
Q2 2020	416,590	$120,940	$271.12	$222.39 - $299.21
Q1 2020	362,964	$86,373	$229.39	$197.47 - $249.85
Q4 2019	60,647	$13,279	$202.38	$165.23 - $225.66
Q3 2019	57,062	$9,668	$176.91	$165.27 - $188.44
Q2 2019	48,088	$8,818	$174.82	$163.68 - $191.71
Q1 2019	48,737	$8,965	$184.70	$160.95 - $195.81
Q4 2018	68,752	$11,393	$173.27	$151.80 - $194.92
Q3 2018	51,944	$10,012	$178.07	$164.70 - $193.78
Q2 2018	27,967	$4,753	$155.01	$144.07 - $172.00
Q1 2018	32,314	$5,262	$163.34	$146.21 - $178.15
Q4 2017	39,709	$5,951	$148.07	$136.50 - $158.04
Q3 2017	43,760	$6,653	$150.51	$125.50 - $167.86
Q2 2017	116,259	$14,982	$120.38	$107.24 - $137.26
Q1 2017	56,862	$6,218	$88.04	$73.34 - $111.88
Q4 2016	5,505	$406	$81.37	$71.46 - $97.93
Q3 2016	5,015	$437	$94.50	$83.50 - $103.73
Q2 2016	4,915	$423	$86.41	$75.92 - $96.49
Q1 2016	4,595	$365	$90.45	$75.90 - $124.96
Q4 2015	4,535	$571	$120.72	$101.49 - $134.71
Q3 2015	4,525	$471	$128.47	$97.45 - $143.45
Q2 2015	4,325	$534	$125.98	$113.68 - $137.50
Q1 2015	4,197	$495	$119.81	$103.75 - $136.33
Q4 2014	4,057	$482	$112.63	$96.43 - $124.35
Q3 2014	4,057	$456	$95.21	$84.41 - $116.88
Q2 2014	3,764	$356	$70.12	$59.79 - $98.80
Q1 2014	3,355	$237	$79.20	$67.49 - $87.77
Q4 2013	3,247	$241	$69.64	$58.06 - $78.38
Q3 2013	3,181	$241	$79.58	$73.43 - $89.96