VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

STIFEL FINANCIAL CORP's Holding History (CIK: 0000720672)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 152,447 Value ($000) $69,113 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 142,529 Value ($000) $55,820 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 101,545 Value ($000) $45,207 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 106,991 Value ($000) $51,872 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 124,844 Value ($000) $50,275 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 94,332 Value ($000) $43,872 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 96,647 Value ($000) $45,300 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 103,141 Value ($000) $43,114 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 99,607 Value ($000) $40,529 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 88,416 Value ($000) $30,746 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 92,647 Value ($000) $32,603 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 79,077 Value ($000) $24,915 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 69,763 Value ($000) $20,146 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 63,824 Value ($000) $18,479 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 81,520 Value ($000) $22,972 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 81,543 Value ($000) $21,280 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 96,333 Value ($000) $21,154 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 112,864 Value ($000) $20,472 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 120,907 Value ($000) $24,378 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 109,897 Value ($000) $23,617 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 90,798 Value ($000) $21,459 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 102,943 Value ($000) $28,013 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 102,633 Value ($000) $29,795 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 96,636 Value ($000) $22,885 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 73,016 Value ($000) $15,958 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 68,524 Value ($000) $11,662 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 72,013 Value ($000) $13,139 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 68,142 Value ($000) $12,506 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 66,886 Value ($000) $11,017 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 72,053 Value ($000) $13,928 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 65,361 Value ($000) $11,140 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 68,736 Value ($000) $11,142 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 66,644 Value ($000) $9,954 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 64,901 Value ($000) $9,864 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 55,216 Value ($000) $7,111 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 39,336 Value ($000) $4,308 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 29,987 Value ($000) $2,209 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 17,580 Value ($000) $1,533 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 19,754 Value ($000) $1,700 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 20,391 Value ($000) $1,621 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 23,066 Value ($000) $2,903 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 6,858 Value ($000) $715 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 3,281 Value ($000) $403 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 2,308 Value ($000) $273 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 4,891 Value ($000) $581 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 5,505 Value ($000) $618 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 3,201 Value ($000) $303 Avg Close $70.12 Range $59.79 - $98.80

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	152,447	$69,113	$431.03	$392.50 - $464.44
Q3 2025	142,529	$55,820	$417.92	$362.50 - $484.56
Q2 2025	101,545	$45,207	$460.83	$416.60 - $510.77
Q1 2025	106,991	$51,872	$466.00	$397.25 - $519.68
Q4 2024	124,844	$50,275	$463.53	$377.85 - $519.88
Q3 2024	94,332	$43,872	$480.37	$456.07 - $510.64
Q2 2024	96,647	$45,300	$434.05	$391.01 - $486.43
Q1 2024	103,141	$43,114	$422.74	$403.43 - $448.40
Q4 2023	99,607	$40,529	$369.42	$341.85 - $413.00
Q3 2023	88,416	$30,746	$349.73	$335.82 - $367.00
Q2 2023	92,647	$32,603	$336.94	$313.47 - $354.94
Q1 2023	79,077	$24,915	$299.93	$282.21 - $325.19
Q4 2022	69,763	$20,146	$304.77	$283.58 - $324.75
Q3 2022	63,824	$18,479	$287.72	$271.61 - $305.95
Q2 2022	81,520	$22,972	$267.66	$233.01 - $293.17
Q1 2022	81,543	$21,280	$237.33	$214.66 - $263.58
Q4 2021	96,333	$21,154	$194.45	$176.36 - $224.49
Q3 2021	112,864	$20,472	$195.24	$180.02 - $204.88
Q2 2021	120,907	$24,378	$209.17	$185.33 - $222.78
Q1 2021	109,897	$23,617	$219.65	$204.62 - $242.99
Q4 2020	90,798	$21,459	$229.44	$202.57 - $280.99
Q3 2020	102,943	$28,013	$275.88	$253.97 - $306.08
Q2 2020	102,633	$29,795	$271.12	$222.39 - $299.21
Q1 2020	96,636	$22,885	$229.39	$197.47 - $249.85
Q4 2019	73,016	$15,958	$202.38	$165.23 - $225.66
Q3 2019	68,524	$11,662	$176.91	$165.27 - $188.44
Q2 2019	72,013	$13,139	$174.82	$163.68 - $191.71
Q1 2019	68,142	$12,506	$184.70	$160.95 - $195.81
Q4 2018	66,886	$11,017	$173.27	$151.80 - $194.92
Q3 2018	72,053	$13,928	$178.07	$164.70 - $193.78
Q2 2018	65,361	$11,140	$155.01	$144.07 - $172.00
Q1 2018	68,736	$11,142	$163.34	$146.21 - $178.15
Q4 2017	66,644	$9,954	$148.07	$136.50 - $158.04
Q3 2017	64,901	$9,864	$150.51	$125.50 - $167.86
Q2 2017	55,216	$7,111	$120.38	$107.24 - $137.26
Q1 2017	39,336	$4,308	$88.04	$73.34 - $111.88
Q4 2016	29,987	$2,209	$81.37	$71.46 - $97.93
Q3 2016	17,580	$1,533	$94.50	$83.50 - $103.73
Q2 2016	19,754	$1,700	$86.41	$75.92 - $96.49
Q1 2016	20,391	$1,621	$90.45	$75.90 - $124.96
Q4 2015	23,066	$2,903	$120.72	$101.49 - $134.71
Q3 2015	6,858	$715	$128.47	$97.45 - $143.45
Q2 2015	3,281	$403	$125.98	$113.68 - $137.50
Q1 2015	2,308	$273	$119.81	$103.75 - $136.33
Q4 2014	4,891	$581	$112.63	$96.43 - $124.35
Q3 2014	5,505	$618	$95.21	$84.41 - $116.88
Q2 2014	3,201	$303	$70.12	$59.79 - $98.80