VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

ROMAN BUTLER FULLERTON & CO's Holding History (CIK: 0000733444)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,604 Value ($000) $750 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 1,594 Value ($000) $665 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 3,577 Value ($000) $1,680 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 3,088 Value ($000) $1,545 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 1,567 Value ($000) $695 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 1,650 Value ($000) $799 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 1,651 Value ($000) $811 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 1,646 Value ($000) $658 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 1,345 Value ($000) $578 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 5,487 Value ($000) $2,036 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 5,897 Value ($000) $2,114 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 5,441 Value ($000) $1,806 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 5,933 Value ($000) $1,851 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 6,005 Value ($000) $1,773 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 6,607 Value ($000) $1,935 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 1,330 Value ($000) $347 Avg Close $237.33 Range $214.66 - $263.58

Q2 2021

Shares 1,185 Value ($000) $239 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 962 Value ($000) $213 Avg Close $219.65 Range $204.62 - $242.99

Q3 2020

Shares 4,008 Value ($000) $1,091 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 4,345 Value ($000) $1,261 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 4,307 Value ($000) $1,025 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 2,126 Value ($000) $465 Avg Close $202.38 Range $165.23 - $225.66

Q4 2018

Shares 2,405 Value ($000) $447 Avg Close $173.27 Range $151.80 - $194.92

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,604	$750	$431.03	$392.50 - $464.44
Q3 2025	1,594	$665	$417.92	$362.50 - $484.56
Q2 2025	3,577	$1,680	$460.83	$416.60 - $510.77
Q1 2025	3,088	$1,545	$466.00	$397.25 - $519.68
Q4 2024	1,567	$695	$463.53	$377.85 - $519.88
Q3 2024	1,650	$799	$480.37	$456.07 - $510.64
Q2 2024	1,651	$811	$434.05	$391.01 - $486.43
Q1 2024	1,646	$658	$422.74	$403.43 - $448.40
Q4 2023	1,345	$578	$369.42	$341.85 - $413.00
Q3 2023	5,487	$2,036	$349.73	$335.82 - $367.00
Q2 2023	5,897	$2,114	$336.94	$313.47 - $354.94
Q1 2023	5,441	$1,806	$299.93	$282.21 - $325.19
Q4 2022	5,933	$1,851	$304.77	$283.58 - $324.75
Q3 2022	6,005	$1,773	$287.72	$271.61 - $305.95
Q2 2022	6,607	$1,935	$267.66	$233.01 - $293.17
Q1 2022	1,330	$347	$237.33	$214.66 - $263.58
Q2 2021	1,185	$239	$209.17	$185.33 - $222.78
Q1 2021	962	$213	$219.65	$204.62 - $242.99
Q3 2020	4,008	$1,091	$275.88	$253.97 - $306.08
Q2 2020	4,345	$1,261	$271.12	$222.39 - $299.21
Q1 2020	4,307	$1,025	$229.39	$197.47 - $249.85
Q4 2019	2,126	$465	$202.38	$165.23 - $225.66
Q4 2018	2,405	$447	$173.27	$151.80 - $194.92