VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

STEPHENS INC /AR/'s Holding History (CIK: 0000757657)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,094 Value ($000) $1,403 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 3,564 Value ($000) $1,396 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 3,392 Value ($000) $1,510 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 3,315 Value ($000) $1,607 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 3,453 Value ($000) $1,391 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 3,548 Value ($000) $1,650 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 3,708 Value ($000) $1,738 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 4,068 Value ($000) $1,700 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 4,025 Value ($000) $1,638 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 4,345 Value ($000) $1,511 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 4,404 Value ($000) $1,550 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 4,704 Value ($000) $1,482 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 4,430 Value ($000) $1,279 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 4,704 Value ($000) $1,362 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 6,459 Value ($000) $1,820 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 7,459 Value ($000) $1,947 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 11,503 Value ($000) $2,526 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 13,999 Value ($000) $2,539 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 17,587 Value ($000) $3,546 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 17,661 Value ($000) $3,795 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 15,603 Value ($000) $3,688 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 12,873 Value ($000) $3,503 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 10,934 Value ($000) $3,174 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 8,469 Value ($000) $2,015 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 8,680 Value ($000) $1,900 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 10,660 Value ($000) $1,806 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 10,969 Value ($000) $2,011 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 11,340 Value ($000) $2,086 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 11,873 Value ($000) $1,967 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 11,673 Value ($000) $2,250 Avg Close $178.07 Range $164.70 - $193.78

Q2 2017

Shares 13,315 Value ($000) $1,716 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 13,172 Value ($000) $1,440 Avg Close $88.04 Range $73.34 - $111.88

Q2 2013

Shares 2,920 Value ($000) $234 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,094	$1,403	$431.03	$392.50 - $464.44
Q3 2025	3,564	$1,396	$417.92	$362.50 - $484.56
Q2 2025	3,392	$1,510	$460.83	$416.60 - $510.77
Q1 2025	3,315	$1,607	$466.00	$397.25 - $519.68
Q4 2024	3,453	$1,391	$463.53	$377.85 - $519.88
Q3 2024	3,548	$1,650	$480.37	$456.07 - $510.64
Q2 2024	3,708	$1,738	$434.05	$391.01 - $486.43
Q1 2024	4,068	$1,700	$422.74	$403.43 - $448.40
Q4 2023	4,025	$1,638	$369.42	$341.85 - $413.00
Q3 2023	4,345	$1,511	$349.73	$335.82 - $367.00
Q2 2023	4,404	$1,550	$336.94	$313.47 - $354.94
Q1 2023	4,704	$1,482	$299.93	$282.21 - $325.19
Q4 2022	4,430	$1,279	$304.77	$283.58 - $324.75
Q3 2022	4,704	$1,362	$287.72	$271.61 - $305.95
Q2 2022	6,459	$1,820	$267.66	$233.01 - $293.17
Q1 2022	7,459	$1,947	$237.33	$214.66 - $263.58
Q4 2021	11,503	$2,526	$194.45	$176.36 - $224.49
Q3 2021	13,999	$2,539	$195.24	$180.02 - $204.88
Q2 2021	17,587	$3,546	$209.17	$185.33 - $222.78
Q1 2021	17,661	$3,795	$219.65	$204.62 - $242.99
Q4 2020	15,603	$3,688	$229.44	$202.57 - $280.99
Q3 2020	12,873	$3,503	$275.88	$253.97 - $306.08
Q2 2020	10,934	$3,174	$271.12	$222.39 - $299.21
Q1 2020	8,469	$2,015	$229.39	$197.47 - $249.85
Q4 2019	8,680	$1,900	$202.38	$165.23 - $225.66
Q3 2019	10,660	$1,806	$176.91	$165.27 - $188.44
Q2 2019	10,969	$2,011	$174.82	$163.68 - $191.71
Q1 2019	11,340	$2,086	$184.70	$160.95 - $195.81
Q4 2018	11,873	$1,967	$173.27	$151.80 - $194.92
Q3 2018	11,673	$2,250	$178.07	$164.70 - $193.78
Q2 2017	13,315	$1,716	$120.38	$107.24 - $137.26
Q1 2017	13,172	$1,440	$88.04	$73.34 - $111.88
Q2 2013	2,920	$234	$73.64	$51.28 - $87.47