VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

NEW YORK STATE COMMON RETIREMENT FUND's Holding History (CIK: 0000810265)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 297,414 Value ($000) $134,836 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 308,577 Value ($000) $120,851 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 340,272 Value ($000) $151,489 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 345,796 Value ($000) $167,649 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 362,334 Value ($000) $145,912 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 359,479 Value ($000) $167,186 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 388,552 Value ($000) $182,122 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 391,856 Value ($000) $163,800 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 409,026 Value ($000) $166,429 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 441,734 Value ($000) $153,609 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 469,193 Value ($000) $165,114 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 461,814 Value ($000) $145,504 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 472,718 Value ($000) $136,512 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 470,490 Value ($000) $136,226 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 490,732 Value ($000) $138,283 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 486,410 Value ($000) $126,938 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 489,848 Value ($000) $107,571 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 503,383 Value ($000) $91,309 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 497,135 Value ($000) $100,237 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 491,547 Value ($000) $105,629 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 511,600 Value ($000) $120,912 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 539,400 Value ($000) $146,782 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 565,530 Value ($000) $164,179 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 569,255 Value ($000) $135,454 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 570,375 Value ($000) $124,884 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 581,575 Value ($000) $98,530 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 576,575 Value ($000) $105,732 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 659,580 Value ($000) $121,330 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 712,480 Value ($000) $118,065 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 757,380 Value ($000) $145,977 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 777,080 Value ($000) $132,073 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 797,980 Value ($000) $130,055 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 840,331 Value ($000) $125,932 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 822,531 Value ($000) $125,058 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 795,047 Value ($000) $102,458 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 751,201 Value ($000) $82,144 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 763,300 Value ($000) $56,232 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 759,700 Value ($000) $66,253 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 757,400 Value ($000) $65,152 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 697,700 Value ($000) $55,460 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 629,800 Value ($000) $79,248 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 651,800 Value ($000) $67,878 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 648,565 Value ($000) $80,085 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 657,875 Value ($000) $77,610 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 654,400 Value ($000) $77,743 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 698,039 Value ($000) $78,397 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 715,425 Value ($000) $67,736 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 737,425 Value ($000) $52,151 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 737,425 Value ($000) $54,791 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 833,725 Value ($000) $63,213 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 700,525 Value ($000) $55,951 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	297,414	$134,836	$431.03	$392.50 - $464.44
Q3 2025	308,577	$120,851	$417.92	$362.50 - $484.56
Q2 2025	340,272	$151,489	$460.83	$416.60 - $510.77
Q1 2025	345,796	$167,649	$466.00	$397.25 - $519.68
Q4 2024	362,334	$145,912	$463.53	$377.85 - $519.88
Q3 2024	359,479	$167,186	$480.37	$456.07 - $510.64
Q2 2024	388,552	$182,122	$434.05	$391.01 - $486.43
Q1 2024	391,856	$163,800	$422.74	$403.43 - $448.40
Q4 2023	409,026	$166,429	$369.42	$341.85 - $413.00
Q3 2023	441,734	$153,609	$349.73	$335.82 - $367.00
Q2 2023	469,193	$165,114	$336.94	$313.47 - $354.94
Q1 2023	461,814	$145,504	$299.93	$282.21 - $325.19
Q4 2022	472,718	$136,512	$304.77	$283.58 - $324.75
Q3 2022	470,490	$136,226	$287.72	$271.61 - $305.95
Q2 2022	490,732	$138,283	$267.66	$233.01 - $293.17
Q1 2022	486,410	$126,938	$237.33	$214.66 - $263.58
Q4 2021	489,848	$107,571	$194.45	$176.36 - $224.49
Q3 2021	503,383	$91,309	$195.24	$180.02 - $204.88
Q2 2021	497,135	$100,237	$209.17	$185.33 - $222.78
Q1 2021	491,547	$105,629	$219.65	$204.62 - $242.99
Q4 2020	511,600	$120,912	$229.44	$202.57 - $280.99
Q3 2020	539,400	$146,782	$275.88	$253.97 - $306.08
Q2 2020	565,530	$164,179	$271.12	$222.39 - $299.21
Q1 2020	569,255	$135,454	$229.39	$197.47 - $249.85
Q4 2019	570,375	$124,884	$202.38	$165.23 - $225.66
Q3 2019	581,575	$98,530	$176.91	$165.27 - $188.44
Q2 2019	576,575	$105,732	$174.82	$163.68 - $191.71
Q1 2019	659,580	$121,330	$184.70	$160.95 - $195.81
Q4 2018	712,480	$118,065	$173.27	$151.80 - $194.92
Q3 2018	757,380	$145,977	$178.07	$164.70 - $193.78
Q2 2018	777,080	$132,073	$155.01	$144.07 - $172.00
Q1 2018	797,980	$130,055	$163.34	$146.21 - $178.15
Q4 2017	840,331	$125,932	$148.07	$136.50 - $158.04
Q3 2017	822,531	$125,058	$150.51	$125.50 - $167.86
Q2 2017	795,047	$102,458	$120.38	$107.24 - $137.26
Q1 2017	751,201	$82,144	$88.04	$73.34 - $111.88
Q4 2016	763,300	$56,232	$81.37	$71.46 - $97.93
Q3 2016	759,700	$66,253	$94.50	$83.50 - $103.73
Q2 2016	757,400	$65,152	$86.41	$75.92 - $96.49
Q1 2016	697,700	$55,460	$90.45	$75.90 - $124.96
Q4 2015	629,800	$79,248	$120.72	$101.49 - $134.71
Q3 2015	651,800	$67,878	$128.47	$97.45 - $143.45
Q2 2015	648,565	$80,085	$125.98	$113.68 - $137.50
Q1 2015	657,875	$77,610	$119.81	$103.75 - $136.33
Q4 2014	654,400	$77,743	$112.63	$96.43 - $124.35
Q3 2014	698,039	$78,397	$95.21	$84.41 - $116.88
Q2 2014	715,425	$67,736	$70.12	$59.79 - $98.80
Q1 2014	737,425	$52,151	$79.20	$67.49 - $87.77
Q4 2013	737,425	$54,791	$69.64	$58.06 - $78.38
Q3 2013	833,725	$63,213	$79.58	$73.43 - $89.96
Q2 2013	700,525	$55,951	$73.64	$51.28 - $87.47