VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

MIZUHO SECURITIES USA LLC's Holding History (CIK: 0000812291)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 18,474 Value ($000) $8,011 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 18,674 Value ($000) $7,302 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 17,750 Value ($000) $7,902 Avg Close $460.83 Range $416.60 - $510.77

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	18,474	$8,011	$431.03	$392.50 - $464.44
Q3 2025	18,674	$7,302	$417.92	$362.50 - $484.56
Q2 2025	17,750	$7,902	$460.83	$416.60 - $510.77