VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

STRS OHIO's Holding History (CIK: 0000820478)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 78,278 Value ($000) $35,488 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 80,625 Value ($000) $31,576 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 112,758 Value ($000) $50,200 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 77,851 Value ($000) $37,744 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 78,531 Value ($000) $31,624 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 88,338 Value ($000) $41,084 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 89,709 Value ($000) $42,048 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 92,938 Value ($000) $39 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 97,953 Value ($000) $40 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 102,114 Value ($000) $36 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 105,125 Value ($000) $37 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 109,469 Value ($000) $34 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 109,338 Value ($000) $32 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 115,695 Value ($000) $33,498 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 116,281 Value ($000) $32,766 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 117,638 Value ($000) $30,699 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 109,431 Value ($000) $24,031 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 112,119 Value ($000) $20,337 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 119,580 Value ($000) $24,110 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 120,139 Value ($000) $25,816 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 130,298 Value ($000) $30,794 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 283,492 Value ($000) $77,143 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 313,724 Value ($000) $91,077 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 325,409 Value ($000) $77,431 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 332,675 Value ($000) $72,839 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 339,921 Value ($000) $57,589 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 341,967 Value ($000) $62,709 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 341,683 Value ($000) $62,852 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 341,105 Value ($000) $56,524 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 340,049 Value ($000) $65,541 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 372,242 Value ($000) $63,266 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 382,171 Value ($000) $62,286 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 391,821 Value ($000) $58,718 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 378,589 Value ($000) $57,560 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 339,865 Value ($000) $43,798 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 334,041 Value ($000) $36,527 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 337,715 Value ($000) $24,879 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 363,319 Value ($000) $31,685 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 346,339 Value ($000) $29,792 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 315,098 Value ($000) $25,047 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 299,567 Value ($000) $37,694 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 299,388 Value ($000) $31,178 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 298,156 Value ($000) $36,816 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 287,069 Value ($000) $33,865 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 6,641 Value ($000) $789 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 2,356 Value ($000) $265 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 2,356 Value ($000) $223 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 2,356 Value ($000) $167 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 2,356 Value ($000) $175 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 2,356 Value ($000) $179 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 208 Value ($000) $17 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	78,278	$35,488	$431.03	$392.50 - $464.44
Q3 2025	80,625	$31,576	$417.92	$362.50 - $484.56
Q2 2025	112,758	$50,200	$460.83	$416.60 - $510.77
Q1 2025	77,851	$37,744	$466.00	$397.25 - $519.68
Q4 2024	78,531	$31,624	$463.53	$377.85 - $519.88
Q3 2024	88,338	$41,084	$480.37	$456.07 - $510.64
Q2 2024	89,709	$42,048	$434.05	$391.01 - $486.43
Q1 2024	92,938	$39	$422.74	$403.43 - $448.40
Q4 2023	97,953	$40	$369.42	$341.85 - $413.00
Q3 2023	102,114	$36	$349.73	$335.82 - $367.00
Q2 2023	105,125	$37	$336.94	$313.47 - $354.94
Q1 2023	109,469	$34	$299.93	$282.21 - $325.19
Q4 2022	109,338	$32	$304.77	$283.58 - $324.75
Q3 2022	115,695	$33,498	$287.72	$271.61 - $305.95
Q2 2022	116,281	$32,766	$267.66	$233.01 - $293.17
Q1 2022	117,638	$30,699	$237.33	$214.66 - $263.58
Q4 2021	109,431	$24,031	$194.45	$176.36 - $224.49
Q3 2021	112,119	$20,337	$195.24	$180.02 - $204.88
Q2 2021	119,580	$24,110	$209.17	$185.33 - $222.78
Q1 2021	120,139	$25,816	$219.65	$204.62 - $242.99
Q4 2020	130,298	$30,794	$229.44	$202.57 - $280.99
Q3 2020	283,492	$77,143	$275.88	$253.97 - $306.08
Q2 2020	313,724	$91,077	$271.12	$222.39 - $299.21
Q1 2020	325,409	$77,431	$229.39	$197.47 - $249.85
Q4 2019	332,675	$72,839	$202.38	$165.23 - $225.66
Q3 2019	339,921	$57,589	$176.91	$165.27 - $188.44
Q2 2019	341,967	$62,709	$174.82	$163.68 - $191.71
Q1 2019	341,683	$62,852	$184.70	$160.95 - $195.81
Q4 2018	341,105	$56,524	$173.27	$151.80 - $194.92
Q3 2018	340,049	$65,541	$178.07	$164.70 - $193.78
Q2 2018	372,242	$63,266	$155.01	$144.07 - $172.00
Q1 2018	382,171	$62,286	$163.34	$146.21 - $178.15
Q4 2017	391,821	$58,718	$148.07	$136.50 - $158.04
Q3 2017	378,589	$57,560	$150.51	$125.50 - $167.86
Q2 2017	339,865	$43,798	$120.38	$107.24 - $137.26
Q1 2017	334,041	$36,527	$88.04	$73.34 - $111.88
Q4 2016	337,715	$24,879	$81.37	$71.46 - $97.93
Q3 2016	363,319	$31,685	$94.50	$83.50 - $103.73
Q2 2016	346,339	$29,792	$86.41	$75.92 - $96.49
Q1 2016	315,098	$25,047	$90.45	$75.90 - $124.96
Q4 2015	299,567	$37,694	$120.72	$101.49 - $134.71
Q3 2015	299,388	$31,178	$128.47	$97.45 - $143.45
Q2 2015	298,156	$36,816	$125.98	$113.68 - $137.50
Q1 2015	287,069	$33,865	$119.81	$103.75 - $136.33
Q4 2014	6,641	$789	$112.63	$96.43 - $124.35
Q3 2014	2,356	$265	$95.21	$84.41 - $116.88
Q2 2014	2,356	$223	$70.12	$59.79 - $98.80
Q1 2014	2,356	$167	$79.20	$67.49 - $87.77
Q4 2013	2,356	$175	$69.64	$58.06 - $78.38
Q3 2013	2,356	$179	$79.58	$73.43 - $89.96
Q2 2013	208	$17	$73.64	$51.28 - $87.47