VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

JOHNSON INVESTMENT COUNSEL INC's Holding History (CIK: 0000821197)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 7,726 Value ($000) $3,503 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 7,730 Value ($000) $3,028 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 7,748 Value ($000) $3,450 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 7,919 Value ($000) $3,839 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 7,883 Value ($000) $3,174 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 7,820 Value ($000) $3,637 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 7,881 Value ($000) $3,694 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 7,873 Value ($000) $3,291 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 9,439 Value ($000) $3,841 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 8,388 Value ($000) $2,917 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 8,380 Value ($000) $2,949 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 8,536 Value ($000) $2,689 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 8,769 Value ($000) $2,532 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 9,240 Value ($000) $2,675 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 9,808 Value ($000) $2,764 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 10,049 Value ($000) $2,622 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 8,455 Value ($000) $1,857 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 8,963 Value ($000) $1,626 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 9,122 Value ($000) $1,839 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 9,049 Value ($000) $1,945 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 9,062 Value ($000) $2,142 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 8,998 Value ($000) $2,449 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 8,992 Value ($000) $2,610 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 9,347 Value ($000) $2,224 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 9,410 Value ($000) $2,060 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 9,776 Value ($000) $1,656 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 10,114 Value ($000) $1,854 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 9,872 Value ($000) $1,815 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 10,032 Value ($000) $1,662 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 10,146 Value ($000) $1,955 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 10,296 Value ($000) $1,749 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 10,312 Value ($000) $1,680 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 10,267 Value ($000) $1,538 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 10,438 Value ($000) $1,586 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 13,461 Value ($000) $1,734 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 15,173 Value ($000) $1,659 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 19,830 Value ($000) $1,460 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 26,037 Value ($000) $2,270 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 28,914 Value ($000) $2,487 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 32,004 Value ($000) $2,543 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 32,869 Value ($000) $4,135 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 35,290 Value ($000) $3,675 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 124,317 Value ($000) $15,350 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 172,422 Value ($000) $20,340 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 182,623 Value ($000) $21,695 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 208,283 Value ($000) $23,392 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 208,243 Value ($000) $19,716 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 7,530 Value ($000) $532 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 7,930 Value ($000) $589 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 8,500 Value ($000) $644 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 11,935 Value ($000) $955 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	7,726	$3,503	$431.03	$392.50 - $464.44
Q3 2025	7,730	$3,028	$417.92	$362.50 - $484.56
Q2 2025	7,748	$3,450	$460.83	$416.60 - $510.77
Q1 2025	7,919	$3,839	$466.00	$397.25 - $519.68
Q4 2024	7,883	$3,174	$463.53	$377.85 - $519.88
Q3 2024	7,820	$3,637	$480.37	$456.07 - $510.64
Q2 2024	7,881	$3,694	$434.05	$391.01 - $486.43
Q1 2024	7,873	$3,291	$422.74	$403.43 - $448.40
Q4 2023	9,439	$3,841	$369.42	$341.85 - $413.00
Q3 2023	8,388	$2,917	$349.73	$335.82 - $367.00
Q2 2023	8,380	$2,949	$336.94	$313.47 - $354.94
Q1 2023	8,536	$2,689	$299.93	$282.21 - $325.19
Q4 2022	8,769	$2,532	$304.77	$283.58 - $324.75
Q3 2022	9,240	$2,675	$287.72	$271.61 - $305.95
Q2 2022	9,808	$2,764	$267.66	$233.01 - $293.17
Q1 2022	10,049	$2,622	$237.33	$214.66 - $263.58
Q4 2021	8,455	$1,857	$194.45	$176.36 - $224.49
Q3 2021	8,963	$1,626	$195.24	$180.02 - $204.88
Q2 2021	9,122	$1,839	$209.17	$185.33 - $222.78
Q1 2021	9,049	$1,945	$219.65	$204.62 - $242.99
Q4 2020	9,062	$2,142	$229.44	$202.57 - $280.99
Q3 2020	8,998	$2,449	$275.88	$253.97 - $306.08
Q2 2020	8,992	$2,610	$271.12	$222.39 - $299.21
Q1 2020	9,347	$2,224	$229.39	$197.47 - $249.85
Q4 2019	9,410	$2,060	$202.38	$165.23 - $225.66
Q3 2019	9,776	$1,656	$176.91	$165.27 - $188.44
Q2 2019	10,114	$1,854	$174.82	$163.68 - $191.71
Q1 2019	9,872	$1,815	$184.70	$160.95 - $195.81
Q4 2018	10,032	$1,662	$173.27	$151.80 - $194.92
Q3 2018	10,146	$1,955	$178.07	$164.70 - $193.78
Q2 2018	10,296	$1,749	$155.01	$144.07 - $172.00
Q1 2018	10,312	$1,680	$163.34	$146.21 - $178.15
Q4 2017	10,267	$1,538	$148.07	$136.50 - $158.04
Q3 2017	10,438	$1,586	$150.51	$125.50 - $167.86
Q2 2017	13,461	$1,734	$120.38	$107.24 - $137.26
Q1 2017	15,173	$1,659	$88.04	$73.34 - $111.88
Q4 2016	19,830	$1,460	$81.37	$71.46 - $97.93
Q3 2016	26,037	$2,270	$94.50	$83.50 - $103.73
Q2 2016	28,914	$2,487	$86.41	$75.92 - $96.49
Q1 2016	32,004	$2,543	$90.45	$75.90 - $124.96
Q4 2015	32,869	$4,135	$120.72	$101.49 - $134.71
Q3 2015	35,290	$3,675	$128.47	$97.45 - $143.45
Q2 2015	124,317	$15,350	$125.98	$113.68 - $137.50
Q1 2015	172,422	$20,340	$119.81	$103.75 - $136.33
Q4 2014	182,623	$21,695	$112.63	$96.43 - $124.35
Q3 2014	208,283	$23,392	$95.21	$84.41 - $116.88
Q2 2014	208,243	$19,716	$70.12	$59.79 - $98.80
Q1 2014	7,530	$532	$79.20	$67.49 - $87.77
Q4 2013	7,930	$589	$69.64	$58.06 - $78.38
Q3 2013	8,500	$644	$79.58	$73.43 - $89.96
Q2 2013	11,935	$955	$73.64	$51.28 - $87.47