VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

PANAGORA ASSET MANAGEMENT INC's Holding History (CIK: 0000883677)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,485 Value ($000) $1,580 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 3,408 Value ($000) $1,335 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 3,408 Value ($000) $1,517 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 3,419 Value ($000) $1,658 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 3,425 Value ($000) $1,379 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 13,335 Value ($000) $6,202 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 48,554 Value ($000) $22,758 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 100,170 Value ($000) $41,872 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 234,131 Value ($000) $95,266 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 201,519 Value ($000) $70,076 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 95,911 Value ($000) $33,752 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 35,416 Value ($000) $11,159 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 110,942 Value ($000) $32,038 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 76,057 Value ($000) $22,022 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 76,079 Value ($000) $21,438 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 184,997 Value ($000) $48,279 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 274,260 Value ($000) $60,227 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 389,888 Value ($000) $70,722 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 298,908 Value ($000) $60,269 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 227,431 Value ($000) $48,873 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 42,094 Value ($000) $9,948 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 92,041 Value ($000) $25,046 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 77,673 Value ($000) $22,549 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 77,576 Value ($000) $18,459 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 78,129 Value ($000) $17,106 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 260,820 Value ($000) $44,188 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 739,528 Value ($000) $135,615 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 856,292 Value ($000) $157,515 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 1,335,889 Value ($000) $221,370 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 1,454,564 Value ($000) $280,353 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 955,545 Value ($000) $162,404 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 882,185 Value ($000) $143,779 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 820,631 Value ($000) $122,980 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 758,328 Value ($000) $115,296 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 613,186 Value ($000) $79,021 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 449,553 Value ($000) $49,159 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 450,000 Value ($000) $33,152 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 431,936 Value ($000) $37,669 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 436,273 Value ($000) $37,528 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 448,912 Value ($000) $35,684 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 455,678 Value ($000) $57,338 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 455,862 Value ($000) $47,473 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 411,105 Value ($000) $50,763 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 382,586 Value ($000) $45,134 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 348,667 Value ($000) $41,422 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 226,950 Value ($000) $25,489 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 27,340 Value ($000) $2,589 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 33,737 Value ($000) $2,386 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 20,628 Value ($000) $1,533 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 16,825 Value ($000) $1,276 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 29,131 Value ($000) $2,327 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,485	$1,580	$431.03	$392.50 - $464.44
Q3 2025	3,408	$1,335	$417.92	$362.50 - $484.56
Q2 2025	3,408	$1,517	$460.83	$416.60 - $510.77
Q1 2025	3,419	$1,658	$466.00	$397.25 - $519.68
Q4 2024	3,425	$1,379	$463.53	$377.85 - $519.88
Q3 2024	13,335	$6,202	$480.37	$456.07 - $510.64
Q2 2024	48,554	$22,758	$434.05	$391.01 - $486.43
Q1 2024	100,170	$41,872	$422.74	$403.43 - $448.40
Q4 2023	234,131	$95,266	$369.42	$341.85 - $413.00
Q3 2023	201,519	$70,076	$349.73	$335.82 - $367.00
Q2 2023	95,911	$33,752	$336.94	$313.47 - $354.94
Q1 2023	35,416	$11,159	$299.93	$282.21 - $325.19
Q4 2022	110,942	$32,038	$304.77	$283.58 - $324.75
Q3 2022	76,057	$22,022	$287.72	$271.61 - $305.95
Q2 2022	76,079	$21,438	$267.66	$233.01 - $293.17
Q1 2022	184,997	$48,279	$237.33	$214.66 - $263.58
Q4 2021	274,260	$60,227	$194.45	$176.36 - $224.49
Q3 2021	389,888	$70,722	$195.24	$180.02 - $204.88
Q2 2021	298,908	$60,269	$209.17	$185.33 - $222.78
Q1 2021	227,431	$48,873	$219.65	$204.62 - $242.99
Q4 2020	42,094	$9,948	$229.44	$202.57 - $280.99
Q3 2020	92,041	$25,046	$275.88	$253.97 - $306.08
Q2 2020	77,673	$22,549	$271.12	$222.39 - $299.21
Q1 2020	77,576	$18,459	$229.39	$197.47 - $249.85
Q4 2019	78,129	$17,106	$202.38	$165.23 - $225.66
Q3 2019	260,820	$44,188	$176.91	$165.27 - $188.44
Q2 2019	739,528	$135,615	$174.82	$163.68 - $191.71
Q1 2019	856,292	$157,515	$184.70	$160.95 - $195.81
Q4 2018	1,335,889	$221,370	$173.27	$151.80 - $194.92
Q3 2018	1,454,564	$280,353	$178.07	$164.70 - $193.78
Q2 2018	955,545	$162,404	$155.01	$144.07 - $172.00
Q1 2018	882,185	$143,779	$163.34	$146.21 - $178.15
Q4 2017	820,631	$122,980	$148.07	$136.50 - $158.04
Q3 2017	758,328	$115,296	$150.51	$125.50 - $167.86
Q2 2017	613,186	$79,021	$120.38	$107.24 - $137.26
Q1 2017	449,553	$49,159	$88.04	$73.34 - $111.88
Q4 2016	450,000	$33,152	$81.37	$71.46 - $97.93
Q3 2016	431,936	$37,669	$94.50	$83.50 - $103.73
Q2 2016	436,273	$37,528	$86.41	$75.92 - $96.49
Q1 2016	448,912	$35,684	$90.45	$75.90 - $124.96
Q4 2015	455,678	$57,338	$120.72	$101.49 - $134.71
Q3 2015	455,862	$47,473	$128.47	$97.45 - $143.45
Q2 2015	411,105	$50,763	$125.98	$113.68 - $137.50
Q1 2015	382,586	$45,134	$119.81	$103.75 - $136.33
Q4 2014	348,667	$41,422	$112.63	$96.43 - $124.35
Q3 2014	226,950	$25,489	$95.21	$84.41 - $116.88
Q2 2014	27,340	$2,589	$70.12	$59.79 - $98.80
Q1 2014	33,737	$2,386	$79.20	$67.49 - $87.77
Q4 2013	20,628	$1,533	$69.64	$58.06 - $78.38
Q3 2013	16,825	$1,276	$79.58	$73.43 - $89.96
Q2 2013	29,131	$2,327	$73.64	$51.28 - $87.47