VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

DAVENPORT & Co LLC's Holding History (CIK: 0000887777)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 211,577 Value ($000) $95,938 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 217,284 Value ($000) $85,289 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 226,184 Value ($000) $100,490 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 225,310 Value ($000) $109,634 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 218,068 Value ($000) $87,643 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 219,709 Value ($000) $102,067 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 221,525 Value ($000) $103,873 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 218,791 Value ($000) $91,334 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 219,238 Value ($000) $89,251 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 115,469 Value ($000) $40,261 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 115,911 Value ($000) $40,694 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 14,344 Value ($000) $4,518 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 14,738 Value ($000) $4,256 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 14,581 Value ($000) $4,223 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 20,865 Value ($000) $5,880 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 22,270 Value ($000) $5,812 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 20,717 Value ($000) $4,549 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 18,399 Value ($000) $3,335 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 17,127 Value ($000) $3,450 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 141,634 Value ($000) $30,436 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 133,036 Value ($000) $31,442 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 1,913 Value ($000) $521 Avg Close $275.88 Range $253.97 - $306.08

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	211,577	$95,938	$431.03	$392.50 - $464.44
Q3 2025	217,284	$85,289	$417.92	$362.50 - $484.56
Q2 2025	226,184	$100,490	$460.83	$416.60 - $510.77
Q1 2025	225,310	$109,634	$466.00	$397.25 - $519.68
Q4 2024	218,068	$87,643	$463.53	$377.85 - $519.88
Q3 2024	219,709	$102,067	$480.37	$456.07 - $510.64
Q2 2024	221,525	$103,873	$434.05	$391.01 - $486.43
Q1 2024	218,791	$91,334	$422.74	$403.43 - $448.40
Q4 2023	219,238	$89,251	$369.42	$341.85 - $413.00
Q3 2023	115,469	$40,261	$349.73	$335.82 - $367.00
Q2 2023	115,911	$40,694	$336.94	$313.47 - $354.94
Q1 2023	14,344	$4,518	$299.93	$282.21 - $325.19
Q4 2022	14,738	$4,256	$304.77	$283.58 - $324.75
Q3 2022	14,581	$4,223	$287.72	$271.61 - $305.95
Q2 2022	20,865	$5,880	$267.66	$233.01 - $293.17
Q1 2022	22,270	$5,812	$237.33	$214.66 - $263.58
Q4 2021	20,717	$4,549	$194.45	$176.36 - $224.49
Q3 2021	18,399	$3,335	$195.24	$180.02 - $204.88
Q2 2021	17,127	$3,450	$209.17	$185.33 - $222.78
Q1 2021	141,634	$30,436	$219.65	$204.62 - $242.99
Q4 2020	133,036	$31,442	$229.44	$202.57 - $280.99
Q3 2020	1,913	$521	$275.88	$253.97 - $306.08