VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

MACKENZIE FINANCIAL CORP's Holding History (CIK: 0000919859)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 63,299 Value ($000) $28,665 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 54,343 Value ($000) $21,283 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 36,275 Value ($000) $16,150 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 36,066 Value ($000) $17,486 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 45,632 Value ($000) $18,088 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 68,692 Value ($000) $31,947 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 84,634 Value ($000) $39,670 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 92,452 Value ($000) $38,646 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 86,827 Value ($000) $35,329 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 82,971 Value ($000) $28,637 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 92,690 Value ($000) $32,216 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 211,083 Value ($000) $66,506 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 108,902 Value ($000) $31,449 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 118,122 Value ($000) $34,201 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 90,042 Value ($000) $25,373 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 99,325 Value ($000) $25,921 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 87,449 Value ($000) $19,204 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 85,553 Value ($000) $15,518 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 81,050 Value ($000) $16,342 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 70,223 Value ($000) $15,090 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 37,821 Value ($000) $8,939 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 24,386 Value ($000) $6,636 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 17,306 Value ($000) $5,024 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 9,454 Value ($000) $2,250 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 4,173 Value ($000) $914 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 1,507 Value ($000) $255 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 1,498 Value ($000) $275 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 31,010 Value ($000) $5,704 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 70,710 Value ($000) $11,717 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 5,149 Value ($000) $992 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 5,006 Value ($000) $851 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 4,015 Value ($000) $654 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 2,240 Value ($000) $336 Avg Close $148.07 Range $136.50 - $158.04

Q3 2016

Shares 13,697 Value ($000) $1,195 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 122,107 Value ($000) $10,504 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 115,951 Value ($000) $9,217 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 73,268 Value ($000) $9,219 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 67,968 Value ($000) $7,078 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 3,200 Value ($000) $395 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 4,400 Value ($000) $519 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 3,800 Value ($000) $451 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 10,400 Value ($000) $1,168 Avg Close $95.21 Range $84.41 - $116.88

Q2 2013

Shares 15,300 Value ($000) $1,225 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	63,299	$28,665	$431.03	$392.50 - $464.44
Q3 2025	54,343	$21,283	$417.92	$362.50 - $484.56
Q2 2025	36,275	$16,150	$460.83	$416.60 - $510.77
Q1 2025	36,066	$17,486	$466.00	$397.25 - $519.68
Q4 2024	45,632	$18,088	$463.53	$377.85 - $519.88
Q3 2024	68,692	$31,947	$480.37	$456.07 - $510.64
Q2 2024	84,634	$39,670	$434.05	$391.01 - $486.43
Q1 2024	92,452	$38,646	$422.74	$403.43 - $448.40
Q4 2023	86,827	$35,329	$369.42	$341.85 - $413.00
Q3 2023	82,971	$28,637	$349.73	$335.82 - $367.00
Q2 2023	92,690	$32,216	$336.94	$313.47 - $354.94
Q1 2023	211,083	$66,506	$299.93	$282.21 - $325.19
Q4 2022	108,902	$31,449	$304.77	$283.58 - $324.75
Q3 2022	118,122	$34,201	$287.72	$271.61 - $305.95
Q2 2022	90,042	$25,373	$267.66	$233.01 - $293.17
Q1 2022	99,325	$25,921	$237.33	$214.66 - $263.58
Q4 2021	87,449	$19,204	$194.45	$176.36 - $224.49
Q3 2021	85,553	$15,518	$195.24	$180.02 - $204.88
Q2 2021	81,050	$16,342	$209.17	$185.33 - $222.78
Q1 2021	70,223	$15,090	$219.65	$204.62 - $242.99
Q4 2020	37,821	$8,939	$229.44	$202.57 - $280.99
Q3 2020	24,386	$6,636	$275.88	$253.97 - $306.08
Q2 2020	17,306	$5,024	$271.12	$222.39 - $299.21
Q1 2020	9,454	$2,250	$229.39	$197.47 - $249.85
Q4 2019	4,173	$914	$202.38	$165.23 - $225.66
Q3 2019	1,507	$255	$176.91	$165.27 - $188.44
Q2 2019	1,498	$275	$174.82	$163.68 - $191.71
Q1 2019	31,010	$5,704	$184.70	$160.95 - $195.81
Q4 2018	70,710	$11,717	$173.27	$151.80 - $194.92
Q3 2018	5,149	$992	$178.07	$164.70 - $193.78
Q2 2018	5,006	$851	$155.01	$144.07 - $172.00
Q1 2018	4,015	$654	$163.34	$146.21 - $178.15
Q4 2017	2,240	$336	$148.07	$136.50 - $158.04
Q3 2016	13,697	$1,195	$94.50	$83.50 - $103.73
Q2 2016	122,107	$10,504	$86.41	$75.92 - $96.49
Q1 2016	115,951	$9,217	$90.45	$75.90 - $124.96
Q4 2015	73,268	$9,219	$120.72	$101.49 - $134.71
Q3 2015	67,968	$7,078	$128.47	$97.45 - $143.45
Q2 2015	3,200	$395	$125.98	$113.68 - $137.50
Q1 2015	4,400	$519	$119.81	$103.75 - $136.33
Q4 2014	3,800	$451	$112.63	$96.43 - $124.35
Q3 2014	10,400	$1,168	$95.21	$84.41 - $116.88
Q2 2013	15,300	$1,225	$73.64	$51.28 - $87.47