VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

TUDOR INVESTMENT CORP ET AL's Holding History (CIK: 0000923093)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,641 Value ($000) $2,557 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 51,374 Value ($000) $20,120 Avg Close $417.92 Range $362.50 - $484.56

Q4 2024

Shares 9,463 Value ($000) $3,811 Avg Close $463.53 Range $377.85 - $519.88

Q1 2024

Shares 23,529 Value ($000) $9,835 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 26,405 Value ($000) $10,744 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 33,355 Value ($000) $11,599 Avg Close $349.73 Range $335.82 - $367.00

Q4 2022

Shares 7,580 Value ($000) $2 Avg Close $304.77 Range $283.58 - $324.75

Q3 2021

Shares 29,658 Value ($000) $5,380 Avg Close $195.24 Range $180.02 - $204.88

Q1 2021

Shares 17,262 Value ($000) $3,709 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 46,303 Value ($000) $10,943 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 5,703 Value ($000) $1,552 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 7,787 Value ($000) $2,261 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 10,372 Value ($000) $2,468 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 15,648 Value ($000) $3,426 Avg Close $202.38 Range $165.23 - $225.66

Q4 2018

Shares 6,359 Value ($000) $1,054 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 8,302 Value ($000) $1,600 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 17,588 Value ($000) $2,989 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 2,431 Value ($000) $396 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 10,416 Value ($000) $1,561 Avg Close $148.07 Range $136.50 - $158.04

Q4 2016

Shares 9,611 Value ($000) $708 Avg Close $81.37 Range $71.46 - $97.93

Q4 2015

Shares 6,286 Value ($000) $791 Avg Close $120.72 Range $101.49 - $134.71

Q2 2015

Shares 2,729 Value ($000) $337 Avg Close $125.98 Range $113.68 - $137.50

Q4 2014

Shares 6,589 Value ($000) $783 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 7,726 Value ($000) $868 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 2,178 Value ($000) $206 Avg Close $70.12 Range $59.79 - $98.80

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,641	$2,557	$431.03	$392.50 - $464.44
Q3 2025	51,374	$20,120	$417.92	$362.50 - $484.56
Q4 2024	9,463	$3,811	$463.53	$377.85 - $519.88
Q1 2024	23,529	$9,835	$422.74	$403.43 - $448.40
Q4 2023	26,405	$10,744	$369.42	$341.85 - $413.00
Q3 2023	33,355	$11,599	$349.73	$335.82 - $367.00
Q4 2022	7,580	$2	$304.77	$283.58 - $324.75
Q3 2021	29,658	$5,380	$195.24	$180.02 - $204.88
Q1 2021	17,262	$3,709	$219.65	$204.62 - $242.99
Q4 2020	46,303	$10,943	$229.44	$202.57 - $280.99
Q3 2020	5,703	$1,552	$275.88	$253.97 - $306.08
Q2 2020	7,787	$2,261	$271.12	$222.39 - $299.21
Q1 2020	10,372	$2,468	$229.39	$197.47 - $249.85
Q4 2019	15,648	$3,426	$202.38	$165.23 - $225.66
Q4 2018	6,359	$1,054	$173.27	$151.80 - $194.92
Q3 2018	8,302	$1,600	$178.07	$164.70 - $193.78
Q2 2018	17,588	$2,989	$155.01	$144.07 - $172.00
Q1 2018	2,431	$396	$163.34	$146.21 - $178.15
Q4 2017	10,416	$1,561	$148.07	$136.50 - $158.04
Q4 2016	9,611	$708	$81.37	$71.46 - $97.93
Q4 2015	6,286	$791	$120.72	$101.49 - $134.71
Q2 2015	2,729	$337	$125.98	$113.68 - $137.50
Q4 2014	6,589	$783	$112.63	$96.43 - $124.35
Q3 2014	7,726	$868	$95.21	$84.41 - $116.88
Q2 2014	2,178	$206	$70.12	$59.79 - $98.80