VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

TORONTO DOMINION BANK's Holding History (CIK: 0000947263)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 91,288 Value ($000) $41,385 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 104,878 Value ($000) $41,082 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 118,626 Value ($000) $52,814 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 99,154 Value ($000) $48,071 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 107,834 Value ($000) $43,424 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 134,202 Value ($000) $62,415 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 131,106 Value ($000) $61,452 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 152,959 Value ($000) $63,938 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 150,009 Value ($000) $61,037 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 136,213 Value ($000) $47,367 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 139,955 Value ($000) $49 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 129,104 Value ($000) $41 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 136,330 Value ($000) $39 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 116,140 Value ($000) $33,611 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 125,949 Value ($000) $35,486 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 131,172 Value ($000) $34,231 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 155,281 Value ($000) $34,097 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 224,515 Value ($000) $40,725 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 191,950 Value ($000) $38,702 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 143,794 Value ($000) $30,899 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 164,855 Value ($000) $38,960 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 151,013 Value ($000) $41,096 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 174,462 Value ($000) $50,652 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 198,387 Value ($000) $47,216 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 243,778 Value ($000) $53,367 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 228,488 Value ($000) $38,705 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 181,947 Value ($000) $33,357 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 181,865 Value ($000) $33,445 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 156,825 Value ($000) $25,983 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 170,915 Value ($000) $32,934 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 167,359 Value ($000) $28,439 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 141,059 Value ($000) $22,985 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 113,159 Value ($000) $16,958 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 99,771 Value ($000) $15,169 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 88,633 Value ($000) $11,420 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 69,896 Value ($000) $7,643 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 45,927 Value ($000) $3,383 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 10,387 Value ($000) $907 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 4,510 Value ($000) $390 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 5,046 Value ($000) $400 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 10,687 Value ($000) $1,346 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 10,945 Value ($000) $1,141 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 9,880 Value ($000) $1,219 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 9,814 Value ($000) $1,158 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 14,495 Value ($000) $1,721 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 9,094 Value ($000) $1,505 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 9,056 Value ($000) $857 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 8,714 Value ($000) $629 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 8,681 Value ($000) $644 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 4,950 Value ($000) $374 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 10,475 Value ($000) $839 Avg Close $73.64 Range $51.28 - $87.47

Q1 2013

Shares 10,475 Value ($000) $576 Avg Close $48.01 Range $42.72 - $55.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	91,288	$41,385	$431.03	$392.50 - $464.44
Q3 2025	104,878	$41,082	$417.92	$362.50 - $484.56
Q2 2025	118,626	$52,814	$460.83	$416.60 - $510.77
Q1 2025	99,154	$48,071	$466.00	$397.25 - $519.68
Q4 2024	107,834	$43,424	$463.53	$377.85 - $519.88
Q3 2024	134,202	$62,415	$480.37	$456.07 - $510.64
Q2 2024	131,106	$61,452	$434.05	$391.01 - $486.43
Q1 2024	152,959	$63,938	$422.74	$403.43 - $448.40
Q4 2023	150,009	$61,037	$369.42	$341.85 - $413.00
Q3 2023	136,213	$47,367	$349.73	$335.82 - $367.00
Q2 2023	139,955	$49	$336.94	$313.47 - $354.94
Q1 2023	129,104	$41	$299.93	$282.21 - $325.19
Q4 2022	136,330	$39	$304.77	$283.58 - $324.75
Q3 2022	116,140	$33,611	$287.72	$271.61 - $305.95
Q2 2022	125,949	$35,486	$267.66	$233.01 - $293.17
Q1 2022	131,172	$34,231	$237.33	$214.66 - $263.58
Q4 2021	155,281	$34,097	$194.45	$176.36 - $224.49
Q3 2021	224,515	$40,725	$195.24	$180.02 - $204.88
Q2 2021	191,950	$38,702	$209.17	$185.33 - $222.78
Q1 2021	143,794	$30,899	$219.65	$204.62 - $242.99
Q4 2020	164,855	$38,960	$229.44	$202.57 - $280.99
Q3 2020	151,013	$41,096	$275.88	$253.97 - $306.08
Q2 2020	174,462	$50,652	$271.12	$222.39 - $299.21
Q1 2020	198,387	$47,216	$229.39	$197.47 - $249.85
Q4 2019	243,778	$53,367	$202.38	$165.23 - $225.66
Q3 2019	228,488	$38,705	$176.91	$165.27 - $188.44
Q2 2019	181,947	$33,357	$174.82	$163.68 - $191.71
Q1 2019	181,865	$33,445	$184.70	$160.95 - $195.81
Q4 2018	156,825	$25,983	$173.27	$151.80 - $194.92
Q3 2018	170,915	$32,934	$178.07	$164.70 - $193.78
Q2 2018	167,359	$28,439	$155.01	$144.07 - $172.00
Q1 2018	141,059	$22,985	$163.34	$146.21 - $178.15
Q4 2017	113,159	$16,958	$148.07	$136.50 - $158.04
Q3 2017	99,771	$15,169	$150.51	$125.50 - $167.86
Q2 2017	88,633	$11,420	$120.38	$107.24 - $137.26
Q1 2017	69,896	$7,643	$88.04	$73.34 - $111.88
Q4 2016	45,927	$3,383	$81.37	$71.46 - $97.93
Q3 2016	10,387	$907	$94.50	$83.50 - $103.73
Q2 2016	4,510	$390	$86.41	$75.92 - $96.49
Q1 2016	5,046	$400	$90.45	$75.90 - $124.96
Q4 2015	10,687	$1,346	$120.72	$101.49 - $134.71
Q3 2015	10,945	$1,141	$128.47	$97.45 - $143.45
Q2 2015	9,880	$1,219	$125.98	$113.68 - $137.50
Q1 2015	9,814	$1,158	$119.81	$103.75 - $136.33
Q4 2014	14,495	$1,721	$112.63	$96.43 - $124.35
Q3 2014	9,094	$1,505	$95.21	$84.41 - $116.88
Q2 2014	9,056	$857	$70.12	$59.79 - $98.80
Q1 2014	8,714	$629	$79.20	$67.49 - $87.77
Q4 2013	8,681	$644	$69.64	$58.06 - $78.38
Q3 2013	4,950	$374	$79.58	$73.43 - $89.96
Q2 2013	10,475	$839	$73.64	$51.28 - $87.47
Q1 2013	10,475	$576	$48.01	$42.72 - $55.93