VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

KINGDON CAPITAL MANAGEMENT, L.L.C.'s Holding History (CIK: 0001000097)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 77,300 Value ($000) $16,975 Avg Close $194.45 Range $176.36 - $224.49

Q4 2017

Shares 57,776 Value ($000) $8,658 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 35,612 Value ($000) $5,414 Avg Close $150.51 Range $125.50 - $167.86

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	77,300	$16,975	$194.45	$176.36 - $224.49
Q4 2017	57,776	$8,658	$148.07	$136.50 - $158.04
Q3 2017	35,612	$5,414	$150.51	$125.50 - $167.86