VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO's Holding History (CIK: 0001007280)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 102,663 Value ($000) $46,543 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 102,732 Value ($000) $40,234 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 106,055 Value ($000) $47,216 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 109,282 Value ($000) $52,982 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 115,847 Value ($000) $46,652 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 121,973 Value ($000) $56,727 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 123,631 Value ($000) $57,948 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 130,024 Value ($000) $54,351 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 139,699 Value ($000) $56,842 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 137,820 Value ($000) $47,926 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 147,255 Value ($000) $51,821 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 153,726 Value ($000) $48,434 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 156,418 Value ($000) $45,170 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 155,501 Value ($000) $45,024 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 154,001 Value ($000) $43,396 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 152,699 Value ($000) $39,850 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 157,009 Value ($000) $34,479 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 164,854 Value ($000) $29,903 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 165,966 Value ($000) $33,464 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 168,761 Value ($000) $36,265 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 155,937 Value ($000) $36,854 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 146,223 Value ($000) $39,790 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 142,367 Value ($000) $41,331 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 143,238 Value ($000) $34,083 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 155,491 Value ($000) $34,045 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 152,852 Value ($000) $25,896 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 152,306 Value ($000) $27,930 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 166,966 Value ($000) $30,713 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 159,775 Value ($000) $26,476 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 171,769 Value ($000) $33,107 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 170,169 Value ($000) $28,922 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 187,321 Value ($000) $30,530 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 195,535 Value ($000) $29,303 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 199,378 Value ($000) $30,313 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 193,666 Value ($000) $24,958 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 192,190 Value ($000) $21,016 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 167,882 Value ($000) $14,403 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 167,701 Value ($000) $14,625 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 167,562 Value ($000) $14,414 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 165,402 Value ($000) $13,148 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 189,802 Value ($000) $23,883 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 177,202 Value ($000) $18,454 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 187,959 Value ($000) $23,209 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 215,337 Value ($000) $25,493 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 107,381 Value ($000) $12,757 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 88,746 Value ($000) $9,967 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 71,258 Value ($000) $6,747 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 75,085 Value ($000) $5,310 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 89,521 Value ($000) $6,651 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 78,312 Value ($000) $5,938 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 59,060 Value ($000) $4,717 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	102,663	$46,543	$431.03	$392.50 - $464.44
Q3 2025	102,732	$40,234	$417.92	$362.50 - $484.56
Q2 2025	106,055	$47,216	$460.83	$416.60 - $510.77
Q1 2025	109,282	$52,982	$466.00	$397.25 - $519.68
Q4 2024	115,847	$46,652	$463.53	$377.85 - $519.88
Q3 2024	121,973	$56,727	$480.37	$456.07 - $510.64
Q2 2024	123,631	$57,948	$434.05	$391.01 - $486.43
Q1 2024	130,024	$54,351	$422.74	$403.43 - $448.40
Q4 2023	139,699	$56,842	$369.42	$341.85 - $413.00
Q3 2023	137,820	$47,926	$349.73	$335.82 - $367.00
Q2 2023	147,255	$51,821	$336.94	$313.47 - $354.94
Q1 2023	153,726	$48,434	$299.93	$282.21 - $325.19
Q4 2022	156,418	$45,170	$304.77	$283.58 - $324.75
Q3 2022	155,501	$45,024	$287.72	$271.61 - $305.95
Q2 2022	154,001	$43,396	$267.66	$233.01 - $293.17
Q1 2022	152,699	$39,850	$237.33	$214.66 - $263.58
Q4 2021	157,009	$34,479	$194.45	$176.36 - $224.49
Q3 2021	164,854	$29,903	$195.24	$180.02 - $204.88
Q2 2021	165,966	$33,464	$209.17	$185.33 - $222.78
Q1 2021	168,761	$36,265	$219.65	$204.62 - $242.99
Q4 2020	155,937	$36,854	$229.44	$202.57 - $280.99
Q3 2020	146,223	$39,790	$275.88	$253.97 - $306.08
Q2 2020	142,367	$41,331	$271.12	$222.39 - $299.21
Q1 2020	143,238	$34,083	$229.39	$197.47 - $249.85
Q4 2019	155,491	$34,045	$202.38	$165.23 - $225.66
Q3 2019	152,852	$25,896	$176.91	$165.27 - $188.44
Q2 2019	152,306	$27,930	$174.82	$163.68 - $191.71
Q1 2019	166,966	$30,713	$184.70	$160.95 - $195.81
Q4 2018	159,775	$26,476	$173.27	$151.80 - $194.92
Q3 2018	171,769	$33,107	$178.07	$164.70 - $193.78
Q2 2018	170,169	$28,922	$155.01	$144.07 - $172.00
Q1 2018	187,321	$30,530	$163.34	$146.21 - $178.15
Q4 2017	195,535	$29,303	$148.07	$136.50 - $158.04
Q3 2017	199,378	$30,313	$150.51	$125.50 - $167.86
Q2 2017	193,666	$24,958	$120.38	$107.24 - $137.26
Q1 2017	192,190	$21,016	$88.04	$73.34 - $111.88
Q4 2016	167,882	$14,403	$81.37	$71.46 - $97.93
Q3 2016	167,701	$14,625	$94.50	$83.50 - $103.73
Q2 2016	167,562	$14,414	$86.41	$75.92 - $96.49
Q1 2016	165,402	$13,148	$90.45	$75.90 - $124.96
Q4 2015	189,802	$23,883	$120.72	$101.49 - $134.71
Q3 2015	177,202	$18,454	$128.47	$97.45 - $143.45
Q2 2015	187,959	$23,209	$125.98	$113.68 - $137.50
Q1 2015	215,337	$25,493	$119.81	$103.75 - $136.33
Q4 2014	107,381	$12,757	$112.63	$96.43 - $124.35
Q3 2014	88,746	$9,967	$95.21	$84.41 - $116.88
Q2 2014	71,258	$6,747	$70.12	$59.79 - $98.80
Q1 2014	75,085	$5,310	$79.20	$67.49 - $87.77
Q4 2013	89,521	$6,651	$69.64	$58.06 - $78.38
Q3 2013	78,312	$5,938	$79.58	$73.43 - $89.96
Q2 2013	59,060	$4,717	$73.64	$51.28 - $87.47