VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

OSTERWEIS CAPITAL MANAGEMENT INC's Holding History (CIK: 0001007524)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 21 Value ($000) $10 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 21 Value ($000) $8 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 21 Value ($000) $9 Avg Close $460.83 Range $416.60 - $510.77

Q3 2022

Shares 6 Value ($000) $2 Avg Close $287.72 Range $271.61 - $305.95

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	21	$10	$431.03	$392.50 - $464.44
Q3 2025	21	$8	$417.92	$362.50 - $484.56
Q2 2025	21	$9	$460.83	$416.60 - $510.77
Q3 2022	6	$2	$287.72	$271.61 - $305.95