VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

PALISADE CAPITAL MANAGEMENT, LP's Holding History (CIK: 0001009006)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 3,593 Value ($000) $424 Avg Close $119.81 Range $103.75 - $136.33
Q4 2014
Shares 3,593 Value ($000) $427 Avg Close $112.63 Range $96.43 - $124.35
Q3 2014
Shares 3,846 Value ($000) $432 Avg Close $95.21 Range $84.41 - $116.88
Q2 2014
Shares 4,016 Value ($000) $380 Avg Close $70.12 Range $59.79 - $98.80
Q1 2014
Shares 4,767 Value ($000) $337 Avg Close $79.20 Range $67.49 - $87.77
Q4 2013
Shares 8,382 Value ($000) $623 Avg Close $69.64 Range $58.06 - $78.38
Q3 2013
Shares 12,870 Value ($000) $976 Avg Close $79.58 Range $73.43 - $89.96
Q2 2013
Shares 14,999 Value ($000) $1,201 Avg Close $73.64 Range $51.28 - $87.47
Q4 2012
Shares 22,291 Value ($000) $934 Avg Close — Range —