VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Sand Hill Global Advisors, LLC's Holding History (CIK: 0001009209)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,176 Value ($000) $2,347 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 6,726 Value ($000) $2,634 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 7,320 Value ($000) $3,259 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 6,925 Value ($000) $3,357 Avg Close $466.00 Range $397.25 - $519.68

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,176	$2,347	$431.03	$392.50 - $464.44
Q3 2025	6,726	$2,634	$417.92	$362.50 - $484.56
Q2 2025	7,320	$3,259	$460.83	$416.60 - $510.77
Q1 2025	6,925	$3,357	$466.00	$397.25 - $519.68