VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Temasek Holdings (Private) Ltd's Holding History (CIK: 0001021944)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018

Shares 244,582 Value ($000) $41,569 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 244,582 Value ($000) $39,862 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 244,582 Value ($000) $36,653 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 244,582 Value ($000) $37,186 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 194,199 Value ($000) $25,026 Avg Close $120.38 Range $107.24 - $137.26

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2018	244,582	$41,569	$155.01	$144.07 - $172.00
Q1 2018	244,582	$39,862	$163.34	$146.21 - $178.15
Q4 2017	244,582	$36,653	$148.07	$136.50 - $158.04
Q3 2017	244,582	$37,186	$150.51	$125.50 - $167.86
Q2 2017	194,199	$25,026	$120.38	$107.24 - $137.26