VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

ING GROEP NV's Holding History (CIK: 0001039765)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 81,129 Value ($000) $36,781 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 11,989 Value ($000) $4,695 Avg Close $417.92 Range $362.50 - $484.56

Q4 2024

Shares 4,784 Value ($000) $1,927 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 53,538 Value ($000) $24,899 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 66,125 Value ($000) $30,994 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 77,043 Value ($000) $32,205 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 75,098 Value ($000) $30,557 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 85,158 Value ($000) $29,613 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 78,413 Value ($000) $27,594 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 44,298 Value ($000) $13,957 Avg Close $299.93 Range $282.21 - $325.19

Q3 2022

Shares 60,025 Value ($000) $17,380 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 56,969 Value ($000) $16,053 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 11,181 Value ($000) $2,918 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 43,987 Value ($000) $9,660 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 26,346 Value ($000) $4,779 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 25,826 Value ($000) $5,207 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 17,212 Value ($000) $3,699 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 17,248 Value ($000) $4,076 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 5,765 Value ($000) $1,569 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 2,193 Value ($000) $637 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 12,700 Value ($000) $3,022 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 1,638 Value ($000) $359 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 16,043 Value ($000) $2,718 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 76,299 Value ($000) $13,992 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 75,865 Value ($000) $13,955 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 66,949 Value ($000) $11,094 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 24,458 Value ($000) $4,714 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 35,251 Value ($000) $5,991 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 43,836 Value ($000) $7,144 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 57,380 Value ($000) $8,599 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 45,874 Value ($000) $6,975 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 54,853 Value ($000) $7,069 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 45,696 Value ($000) $4,997 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 7,416 Value ($000) $552 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 9,435 Value ($000) $802 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 2,376 Value ($000) $204 Avg Close $86.41 Range $75.92 - $96.49

Q1 2015

Shares 9,520 Value ($000) $1,122 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 9,450 Value ($000) $1,123 Avg Close $112.63 Range $96.43 - $124.35

Q3 2013

Shares 240,413 Value ($000) $18,228 Avg Close $79.58 Range $73.43 - $89.96

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	81,129	$36,781	$431.03	$392.50 - $464.44
Q3 2025	11,989	$4,695	$417.92	$362.50 - $484.56
Q4 2024	4,784	$1,927	$463.53	$377.85 - $519.88
Q3 2024	53,538	$24,899	$480.37	$456.07 - $510.64
Q2 2024	66,125	$30,994	$434.05	$391.01 - $486.43
Q1 2024	77,043	$32,205	$422.74	$403.43 - $448.40
Q4 2023	75,098	$30,557	$369.42	$341.85 - $413.00
Q3 2023	85,158	$29,613	$349.73	$335.82 - $367.00
Q2 2023	78,413	$27,594	$336.94	$313.47 - $354.94
Q1 2023	44,298	$13,957	$299.93	$282.21 - $325.19
Q3 2022	60,025	$17,380	$287.72	$271.61 - $305.95
Q2 2022	56,969	$16,053	$267.66	$233.01 - $293.17
Q1 2022	11,181	$2,918	$237.33	$214.66 - $263.58
Q4 2021	43,987	$9,660	$194.45	$176.36 - $224.49
Q3 2021	26,346	$4,779	$195.24	$180.02 - $204.88
Q2 2021	25,826	$5,207	$209.17	$185.33 - $222.78
Q1 2021	17,212	$3,699	$219.65	$204.62 - $242.99
Q4 2020	17,248	$4,076	$229.44	$202.57 - $280.99
Q3 2020	5,765	$1,569	$275.88	$253.97 - $306.08
Q2 2020	2,193	$637	$271.12	$222.39 - $299.21
Q1 2020	12,700	$3,022	$229.39	$197.47 - $249.85
Q4 2019	1,638	$359	$202.38	$165.23 - $225.66
Q3 2019	16,043	$2,718	$176.91	$165.27 - $188.44
Q2 2019	76,299	$13,992	$174.82	$163.68 - $191.71
Q1 2019	75,865	$13,955	$184.70	$160.95 - $195.81
Q4 2018	66,949	$11,094	$173.27	$151.80 - $194.92
Q3 2018	24,458	$4,714	$178.07	$164.70 - $193.78
Q2 2018	35,251	$5,991	$155.01	$144.07 - $172.00
Q1 2018	43,836	$7,144	$163.34	$146.21 - $178.15
Q4 2017	57,380	$8,599	$148.07	$136.50 - $158.04
Q3 2017	45,874	$6,975	$150.51	$125.50 - $167.86
Q2 2017	54,853	$7,069	$120.38	$107.24 - $137.26
Q1 2017	45,696	$4,997	$88.04	$73.34 - $111.88
Q4 2016	7,416	$552	$81.37	$71.46 - $97.93
Q3 2016	9,435	$802	$94.50	$83.50 - $103.73
Q2 2016	2,376	$204	$86.41	$75.92 - $96.49
Q1 2015	9,520	$1,122	$119.81	$103.75 - $136.33
Q4 2014	9,450	$1,123	$112.63	$96.43 - $124.35
Q3 2013	240,413	$18,228	$79.58	$73.43 - $89.96