VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

VICTORY CAPITAL MANAGEMENT INC's Holding History (CIK: 0001040188)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,356,766 Value ($000) $1,521,851 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 2,247,566 Value ($000) $787,317 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 2,155,164 Value ($000) $967,777 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 293,885 Value ($000) $142,481 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 305,146 Value ($000) $122,882 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 310,414 Value ($000) $144,367 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 325,748 Value ($000) $152,685 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 407,654 Value ($000) $170,403 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 435,838 Value ($000) $177,338 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 578,451 Value ($000) $201,151 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 496,836 Value ($000) $174,842 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 546,539 Value ($000) $172,198 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 495,390 Value ($000) $143,059 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 523,524 Value ($000) $151,581 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 549,392 Value ($000) $154,813 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 521,538 Value ($000) $138,280 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 170,494 Value ($000) $37,440 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 165,777 Value ($000) $30,070 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 159,453 Value ($000) $32,151 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 573,278 Value ($000) $123,191 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 657,200 Value ($000) $155,323 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 552,729 Value ($000) $150,408 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 584,876 Value ($000) $169,795 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 524,625 Value ($000) $124,835 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 347,651 Value ($000) $76,118 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 148,256 Value ($000) $25,118 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 19,094 Value ($000) $3,501 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 19,027 Value ($000) $3,500 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 3,769 Value ($000) $625 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 3,794 Value ($000) $731 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 3,840 Value ($000) $653 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 3,920 Value ($000) $639 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 3,995 Value ($000) $599 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 4,161 Value ($000) $633 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 4,291 Value ($000) $553 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 4,520 Value ($000) $494 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 4,664 Value ($000) $344 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 4,731 Value ($000) $413 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 3,157 Value ($000) $272 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 3,225 Value ($000) $256 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 3,310 Value ($000) $416 Avg Close $120.72 Range $101.49 - $134.71

Q3 2013

Shares 4 Value ($000) $0 Avg Close $79.58 Range $73.43 - $89.96

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,356,766	$1,521,851	$431.03	$392.50 - $464.44
Q3 2025	2,247,566	$787,317	$417.92	$362.50 - $484.56
Q2 2025	2,155,164	$967,777	$460.83	$416.60 - $510.77
Q1 2025	293,885	$142,481	$466.00	$397.25 - $519.68
Q4 2024	305,146	$122,882	$463.53	$377.85 - $519.88
Q3 2024	310,414	$144,367	$480.37	$456.07 - $510.64
Q2 2024	325,748	$152,685	$434.05	$391.01 - $486.43
Q1 2024	407,654	$170,403	$422.74	$403.43 - $448.40
Q4 2023	435,838	$177,338	$369.42	$341.85 - $413.00
Q3 2023	578,451	$201,151	$349.73	$335.82 - $367.00
Q2 2023	496,836	$174,842	$336.94	$313.47 - $354.94
Q1 2023	546,539	$172,198	$299.93	$282.21 - $325.19
Q4 2022	495,390	$143,059	$304.77	$283.58 - $324.75
Q3 2022	523,524	$151,581	$287.72	$271.61 - $305.95
Q2 2022	549,392	$154,813	$267.66	$233.01 - $293.17
Q1 2022	521,538	$138,280	$237.33	$214.66 - $263.58
Q4 2021	170,494	$37,440	$194.45	$176.36 - $224.49
Q3 2021	165,777	$30,070	$195.24	$180.02 - $204.88
Q2 2021	159,453	$32,151	$209.17	$185.33 - $222.78
Q1 2021	573,278	$123,191	$219.65	$204.62 - $242.99
Q4 2020	657,200	$155,323	$229.44	$202.57 - $280.99
Q3 2020	552,729	$150,408	$275.88	$253.97 - $306.08
Q2 2020	584,876	$169,795	$271.12	$222.39 - $299.21
Q1 2020	524,625	$124,835	$229.39	$197.47 - $249.85
Q4 2019	347,651	$76,118	$202.38	$165.23 - $225.66
Q3 2019	148,256	$25,118	$176.91	$165.27 - $188.44
Q2 2019	19,094	$3,501	$174.82	$163.68 - $191.71
Q1 2019	19,027	$3,500	$184.70	$160.95 - $195.81
Q4 2018	3,769	$625	$173.27	$151.80 - $194.92
Q3 2018	3,794	$731	$178.07	$164.70 - $193.78
Q2 2018	3,840	$653	$155.01	$144.07 - $172.00
Q1 2018	3,920	$639	$163.34	$146.21 - $178.15
Q4 2017	3,995	$599	$148.07	$136.50 - $158.04
Q3 2017	4,161	$633	$150.51	$125.50 - $167.86
Q2 2017	4,291	$553	$120.38	$107.24 - $137.26
Q1 2017	4,520	$494	$88.04	$73.34 - $111.88
Q4 2016	4,664	$344	$81.37	$71.46 - $97.93
Q3 2016	4,731	$413	$94.50	$83.50 - $103.73
Q2 2016	3,157	$272	$86.41	$75.92 - $96.49
Q1 2016	3,225	$256	$90.45	$75.90 - $124.96
Q4 2015	3,310	$416	$120.72	$101.49 - $134.71
Q3 2013	4	$0	$79.58	$73.43 - $89.96