VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

MARSICO CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001055966)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018

Shares 416,292 Value ($000) $67,847 Avg Close $163.34 Range $146.21 - $178.15

Q3 2015

Shares 1,869,291 Value ($000) $194,668 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 1,950,563 Value ($000) $240,855 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 2,160,116 Value ($000) $254,829 Avg Close $119.81 Range $103.75 - $136.33

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2018	416,292	$67,847	$163.34	$146.21 - $178.15
Q3 2015	1,869,291	$194,668	$128.47	$97.45 - $143.45
Q2 2015	1,950,563	$240,855	$125.98	$113.68 - $137.50
Q1 2015	2,160,116	$254,829	$119.81	$103.75 - $136.33