VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

PARK AVENUE SECURITIES LLC's Holding History (CIK: 0001071640)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 13,807 Value ($000) $6 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 15,043 Value ($000) $6 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 15,362 Value ($000) $7 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 15,339 Value ($000) $7 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 14,454 Value ($000) $6 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 13,987 Value ($000) $7 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 13,999 Value ($000) $7 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 14,239 Value ($000) $6 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 13,142 Value ($000) $5 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 10,481 Value ($000) $4 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 10,933 Value ($000) $4 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 10,191 Value ($000) $3 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 8,678 Value ($000) $2,506 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 7,815 Value ($000) $2,263,000 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 7,710 Value ($000) $2,173 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 8,869 Value ($000) $2,315 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 5,828 Value ($000) $1,280,000 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 6,851 Value ($000) $1,243 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 11,165 Value ($000) $2,251 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 11,543 Value ($000) $2,480 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 6,882 Value ($000) $1,626 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 4,923 Value ($000) $1,340 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 4,133 Value ($000) $1,200 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 3,888 Value ($000) $925 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 3,452 Value ($000) $756 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 3,464 Value ($000) $587 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 3,343 Value ($000) $613 Avg Close $174.82 Range $163.68 - $191.71

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	13,807	$6	$431.03	$392.50 - $464.44
Q3 2025	15,043	$6	$417.92	$362.50 - $484.56
Q2 2025	15,362	$7	$460.83	$416.60 - $510.77
Q1 2025	15,339	$7	$466.00	$397.25 - $519.68
Q4 2024	14,454	$6	$463.53	$377.85 - $519.88
Q3 2024	13,987	$7	$480.37	$456.07 - $510.64
Q2 2024	13,999	$7	$434.05	$391.01 - $486.43
Q1 2024	14,239	$6	$422.74	$403.43 - $448.40
Q4 2023	13,142	$5	$369.42	$341.85 - $413.00
Q3 2023	10,481	$4	$349.73	$335.82 - $367.00
Q2 2023	10,933	$4	$336.94	$313.47 - $354.94
Q1 2023	10,191	$3	$299.93	$282.21 - $325.19
Q4 2022	8,678	$2,506	$304.77	$283.58 - $324.75
Q3 2022	7,815	$2,263,000	$287.72	$271.61 - $305.95
Q2 2022	7,710	$2,173	$267.66	$233.01 - $293.17
Q1 2022	8,869	$2,315	$237.33	$214.66 - $263.58
Q4 2021	5,828	$1,280,000	$194.45	$176.36 - $224.49
Q3 2021	6,851	$1,243	$195.24	$180.02 - $204.88
Q2 2021	11,165	$2,251	$209.17	$185.33 - $222.78
Q1 2021	11,543	$2,480	$219.65	$204.62 - $242.99
Q4 2020	6,882	$1,626	$229.44	$202.57 - $280.99
Q3 2020	4,923	$1,340	$275.88	$253.97 - $306.08
Q2 2020	4,133	$1,200	$271.12	$222.39 - $299.21
Q1 2020	3,888	$925	$229.39	$197.47 - $249.85
Q4 2019	3,452	$756	$202.38	$165.23 - $225.66
Q3 2019	3,464	$587	$176.91	$165.27 - $188.44
Q2 2019	3,343	$613	$174.82	$163.68 - $191.71