VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

D.A. DAVIDSON & CO.'s Holding History (CIK: 0001080107)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,251 Value ($000) $2,381 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 5,097 Value ($000) $1,996 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 4,856 Value ($000) $2,162 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 4,805 Value ($000) $2,330 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 5,154 Value ($000) $2,076 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 5,475 Value ($000) $2,546 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 4,864 Value ($000) $2,280 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 4,886 Value ($000) $2,042 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 2,459 Value ($000) $1,001 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 3,363 Value ($000) $1,169 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 3,253 Value ($000) $1,145 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 3,774 Value ($000) $1,189 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 4,341 Value ($000) $1,254 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 2,101 Value ($000) $608 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 2,242 Value ($000) $632 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 2,181 Value ($000) $569 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 1,233 Value ($000) $271 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 1,236 Value ($000) $224 Avg Close $195.24 Range $180.02 - $204.88

Q1 2021

Shares 932 Value ($000) $200 Avg Close $219.65 Range $204.62 - $242.99

Q3 2020

Shares 841 Value ($000) $229 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 771 Value ($000) $224 Avg Close $271.12 Range $222.39 - $299.21

Q1 2019

Shares 21,676 Value ($000) $3,987 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 22,300 Value ($000) $3,695 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 22,533 Value ($000) $4,343 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 22,739 Value ($000) $3,865 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 23,411 Value ($000) $3,816 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 23,712 Value ($000) $3,553 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 25,038 Value ($000) $3,806 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 24,905 Value ($000) $3,209 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 24,458 Value ($000) $2,674 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 25,098 Value ($000) $1,846 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 16,040 Value ($000) $1,398 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 16,015 Value ($000) $1,376 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 15,678 Value ($000) $1,245 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 14,940 Value ($000) $1,879 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 15,001 Value ($000) $1,561 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 14,867 Value ($000) $1,834 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 14,115 Value ($000) $1,664 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 15,369 Value ($000) $1,825 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 19,941 Value ($000) $2,238 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 20,061 Value ($000) $1,899 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 19,198 Value ($000) $1,356 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 16,521 Value ($000) $1,226 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 11,237 Value ($000) $851 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 10,385 Value ($000) $829 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,251	$2,381	$431.03	$392.50 - $464.44
Q3 2025	5,097	$1,996	$417.92	$362.50 - $484.56
Q2 2025	4,856	$2,162	$460.83	$416.60 - $510.77
Q1 2025	4,805	$2,330	$466.00	$397.25 - $519.68
Q4 2024	5,154	$2,076	$463.53	$377.85 - $519.88
Q3 2024	5,475	$2,546	$480.37	$456.07 - $510.64
Q2 2024	4,864	$2,280	$434.05	$391.01 - $486.43
Q1 2024	4,886	$2,042	$422.74	$403.43 - $448.40
Q4 2023	2,459	$1,001	$369.42	$341.85 - $413.00
Q3 2023	3,363	$1,169	$349.73	$335.82 - $367.00
Q2 2023	3,253	$1,145	$336.94	$313.47 - $354.94
Q1 2023	3,774	$1,189	$299.93	$282.21 - $325.19
Q4 2022	4,341	$1,254	$304.77	$283.58 - $324.75
Q3 2022	2,101	$608	$287.72	$271.61 - $305.95
Q2 2022	2,242	$632	$267.66	$233.01 - $293.17
Q1 2022	2,181	$569	$237.33	$214.66 - $263.58
Q4 2021	1,233	$271	$194.45	$176.36 - $224.49
Q3 2021	1,236	$224	$195.24	$180.02 - $204.88
Q1 2021	932	$200	$219.65	$204.62 - $242.99
Q3 2020	841	$229	$275.88	$253.97 - $306.08
Q2 2020	771	$224	$271.12	$222.39 - $299.21
Q1 2019	21,676	$3,987	$184.70	$160.95 - $195.81
Q4 2018	22,300	$3,695	$173.27	$151.80 - $194.92
Q3 2018	22,533	$4,343	$178.07	$164.70 - $193.78
Q2 2018	22,739	$3,865	$155.01	$144.07 - $172.00
Q1 2018	23,411	$3,816	$163.34	$146.21 - $178.15
Q4 2017	23,712	$3,553	$148.07	$136.50 - $158.04
Q3 2017	25,038	$3,806	$150.51	$125.50 - $167.86
Q2 2017	24,905	$3,209	$120.38	$107.24 - $137.26
Q1 2017	24,458	$2,674	$88.04	$73.34 - $111.88
Q4 2016	25,098	$1,846	$81.37	$71.46 - $97.93
Q3 2016	16,040	$1,398	$94.50	$83.50 - $103.73
Q2 2016	16,015	$1,376	$86.41	$75.92 - $96.49
Q1 2016	15,678	$1,245	$90.45	$75.90 - $124.96
Q4 2015	14,940	$1,879	$120.72	$101.49 - $134.71
Q3 2015	15,001	$1,561	$128.47	$97.45 - $143.45
Q2 2015	14,867	$1,834	$125.98	$113.68 - $137.50
Q1 2015	14,115	$1,664	$119.81	$103.75 - $136.33
Q4 2014	15,369	$1,825	$112.63	$96.43 - $124.35
Q3 2014	19,941	$2,238	$95.21	$84.41 - $116.88
Q2 2014	20,061	$1,899	$70.12	$59.79 - $98.80
Q1 2014	19,198	$1,356	$79.20	$67.49 - $87.77
Q4 2013	16,521	$1,226	$69.64	$58.06 - $78.38
Q3 2013	11,237	$851	$79.58	$73.43 - $89.96
Q2 2013	10,385	$829	$73.64	$51.28 - $87.47