VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

OREGON PUBLIC EMPLOYEES RETIREMENT FUND's Holding History (CIK: 0001107314)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 29,044 Value ($000) $13,167 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 29,285 Value ($000) $11,469 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 22,184 Value ($000) $9,876 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 22,084 Value ($000) $10,707 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 22,074 Value ($000) $8,889 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 22,083 Value ($000) $10,270 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 22,173 Value ($000) $10,393 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 22,073 Value ($000) $9,227 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 37,488 Value ($000) $15,253 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 50,044 Value ($000) $17,402 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 64,480 Value ($000) $22,691 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 94,567 Value ($000) $29,795 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 94,845 Value ($000) $27,389 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 80,274 Value ($000) $23,243 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 84,016 Value ($000) $23,675 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 20,466 Value ($000) $5,341 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 21,040 Value ($000) $4,620 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 21,649 Value ($000) $3,927 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 21,945 Value ($000) $4,425 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 24,606 Value ($000) $5,288 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 24,725 Value ($000) $5,844 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 64,979 Value ($000) $17,682 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 69,508 Value ($000) $20,179 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 79,477 Value ($000) $18,912 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 24,459 Value ($000) $5,355 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 25,884 Value ($000) $4,385 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 27,151 Value ($000) $4,979 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 26,992 Value ($000) $4,965 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 27,825 Value ($000) $4,611 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 27,725 Value ($000) $5,344 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 27,725 Value ($000) $4,712 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 26,589 Value ($000) $4,333 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 26,536 Value ($000) $4,035 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 26,536 Value ($000) $4,035 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 25,793 Value ($000) $3,324 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 25,793 Value ($000) $2,820 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 25,793 Value ($000) $1,900 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 25,226 Value ($000) $2,200 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 25,194 Value ($000) $2,167 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 24,994 Value ($000) $1,987 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 24,158 Value ($000) $3,040 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 24,158 Value ($000) $2,516 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 24,258 Value ($000) $2,995 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 23,658 Value ($000) $2,791 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 23,258 Value ($000) $2,763 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 23,100 Value ($000) $2,594 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 22,800 Value ($000) $2,159 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 22,400 Value ($000) $1,584 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 22,300 Value ($000) $1,657 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 36,235 Value ($000) $2,747 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 47,035 Value ($000) $3,757 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	29,044	$13,167	$431.03	$392.50 - $464.44
Q3 2025	29,285	$11,469	$417.92	$362.50 - $484.56
Q2 2025	22,184	$9,876	$460.83	$416.60 - $510.77
Q1 2025	22,084	$10,707	$466.00	$397.25 - $519.68
Q4 2024	22,074	$8,889	$463.53	$377.85 - $519.88
Q3 2024	22,083	$10,270	$480.37	$456.07 - $510.64
Q2 2024	22,173	$10,393	$434.05	$391.01 - $486.43
Q1 2024	22,073	$9,227	$422.74	$403.43 - $448.40
Q4 2023	37,488	$15,253	$369.42	$341.85 - $413.00
Q3 2023	50,044	$17,402	$349.73	$335.82 - $367.00
Q2 2023	64,480	$22,691	$336.94	$313.47 - $354.94
Q1 2023	94,567	$29,795	$299.93	$282.21 - $325.19
Q4 2022	94,845	$27,389	$304.77	$283.58 - $324.75
Q3 2022	80,274	$23,243	$287.72	$271.61 - $305.95
Q2 2022	84,016	$23,675	$267.66	$233.01 - $293.17
Q1 2022	20,466	$5,341	$237.33	$214.66 - $263.58
Q4 2021	21,040	$4,620	$194.45	$176.36 - $224.49
Q3 2021	21,649	$3,927	$195.24	$180.02 - $204.88
Q2 2021	21,945	$4,425	$209.17	$185.33 - $222.78
Q1 2021	24,606	$5,288	$219.65	$204.62 - $242.99
Q4 2020	24,725	$5,844	$229.44	$202.57 - $280.99
Q3 2020	64,979	$17,682	$275.88	$253.97 - $306.08
Q2 2020	69,508	$20,179	$271.12	$222.39 - $299.21
Q1 2020	79,477	$18,912	$229.39	$197.47 - $249.85
Q4 2019	24,459	$5,355	$202.38	$165.23 - $225.66
Q3 2019	25,884	$4,385	$176.91	$165.27 - $188.44
Q2 2019	27,151	$4,979	$174.82	$163.68 - $191.71
Q1 2019	26,992	$4,965	$184.70	$160.95 - $195.81
Q4 2018	27,825	$4,611	$173.27	$151.80 - $194.92
Q3 2018	27,725	$5,344	$178.07	$164.70 - $193.78
Q2 2018	27,725	$4,712	$155.01	$144.07 - $172.00
Q1 2018	26,589	$4,333	$163.34	$146.21 - $178.15
Q4 2017	26,536	$4,035	$148.07	$136.50 - $158.04
Q3 2017	26,536	$4,035	$150.51	$125.50 - $167.86
Q2 2017	25,793	$3,324	$120.38	$107.24 - $137.26
Q1 2017	25,793	$2,820	$88.04	$73.34 - $111.88
Q4 2016	25,793	$1,900	$81.37	$71.46 - $97.93
Q3 2016	25,226	$2,200	$94.50	$83.50 - $103.73
Q2 2016	25,194	$2,167	$86.41	$75.92 - $96.49
Q1 2016	24,994	$1,987	$90.45	$75.90 - $124.96
Q4 2015	24,158	$3,040	$120.72	$101.49 - $134.71
Q3 2015	24,158	$2,516	$128.47	$97.45 - $143.45
Q2 2015	24,258	$2,995	$125.98	$113.68 - $137.50
Q1 2015	23,658	$2,791	$119.81	$103.75 - $136.33
Q4 2014	23,258	$2,763	$112.63	$96.43 - $124.35
Q3 2014	23,100	$2,594	$95.21	$84.41 - $116.88
Q2 2014	22,800	$2,159	$70.12	$59.79 - $98.80
Q1 2014	22,400	$1,584	$79.20	$67.49 - $87.77
Q4 2013	22,300	$1,657	$69.64	$58.06 - $78.38
Q3 2013	36,235	$2,747	$79.58	$73.43 - $89.96
Q2 2013	47,035	$3,757	$73.64	$51.28 - $87.47