VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

PRENTISS SMITH & CO INC's Holding History (CIK: 0001134687)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016

Shares 3,445 Value ($000) $274 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 500 Value ($000) $63 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 500 Value ($000) $52 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 500 Value ($000) $62 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 500 Value ($000) $59 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 500 Value ($000) $59 Avg Close $112.63 Range $96.43 - $124.35

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2016	3,445	$274	$90.45	$75.90 - $124.96
Q4 2015	500	$63	$120.72	$101.49 - $134.71
Q3 2015	500	$52	$128.47	$97.45 - $143.45
Q2 2015	500	$62	$125.98	$113.68 - $137.50
Q1 2015	500	$59	$119.81	$103.75 - $136.33
Q4 2014	500	$59	$112.63	$96.43 - $124.35