VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

LAZARD ASSET MANAGEMENT LLC's Holding History (CIK: 0001207017)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 198,950 Value ($000) $90,196 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 544,823 Value ($000) $213,374 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 480,310 Value ($000) $214 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 532,597 Value ($000) $258 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 526,119 Value ($000) $212 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 7,987 Value ($000) $4 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 122,456 Value ($000) $57 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 123,883 Value ($000) $52 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 119,789 Value ($000) $49 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 118,956 Value ($000) $41 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 119,716 Value ($000) $42 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 127,530 Value ($000) $40 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 142,441 Value ($000) $41 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 623,841 Value ($000) $180,625 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 863,906 Value ($000) $243,438 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 897,842 Value ($000) $234,308 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 915,720 Value ($000) $201,090 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 165,936 Value ($000) $30,098 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 141,741 Value ($000) $28,577 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 115,885 Value ($000) $24,902 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 132,109 Value ($000) $31,221 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 206,182 Value ($000) $56,105 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 200,223 Value ($000) $58,125 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 58,623 Value ($000) $13,948 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 55,359 Value ($000) $12,120 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 54,332 Value ($000) $9,204 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 78,530 Value ($000) $14,400 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 86,227 Value ($000) $15,861 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 33,050 Value ($000) $5,476 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 38,987 Value ($000) $7,514 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 31,735 Value ($000) $5,393 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 159,507 Value ($000) $25,996 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 173,986 Value ($000) $26,073 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 173,422 Value ($000) $26,367 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 201,167 Value ($000) $25,924 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 456,073 Value ($000) $49,871 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 725,404 Value ($000) $53,440 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 1,197,473 Value ($000) $104,429 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 1,265,758 Value ($000) $108,879 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 982,343 Value ($000) $78,085 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 785,410 Value ($000) $98,826 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 1,247,845 Value ($000) $129,949 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 1,931,356 Value ($000) $238,482 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 2,085,541 Value ($000) $246,029 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 2,334,959 Value ($000) $277,391 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 2,524,532 Value ($000) $283,529 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 2,627,189 Value ($000) $248,740 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 2,756,735 Value ($000) $194,955 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 3,342,401 Value ($000) $248,339 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 3,389,304 Value ($000) $256,976 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 3,650,067 Value ($000) $291,529 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	198,950	$90,196	$431.03	$392.50 - $464.44
Q3 2025	544,823	$213,374	$417.92	$362.50 - $484.56
Q2 2025	480,310	$214	$460.83	$416.60 - $510.77
Q1 2025	532,597	$258	$466.00	$397.25 - $519.68
Q4 2024	526,119	$212	$463.53	$377.85 - $519.88
Q3 2024	7,987	$4	$480.37	$456.07 - $510.64
Q2 2024	122,456	$57	$434.05	$391.01 - $486.43
Q1 2024	123,883	$52	$422.74	$403.43 - $448.40
Q4 2023	119,789	$49	$369.42	$341.85 - $413.00
Q3 2023	118,956	$41	$349.73	$335.82 - $367.00
Q2 2023	119,716	$42	$336.94	$313.47 - $354.94
Q1 2023	127,530	$40	$299.93	$282.21 - $325.19
Q4 2022	142,441	$41	$304.77	$283.58 - $324.75
Q3 2022	623,841	$180,625	$287.72	$271.61 - $305.95
Q2 2022	863,906	$243,438	$267.66	$233.01 - $293.17
Q1 2022	897,842	$234,308	$237.33	$214.66 - $263.58
Q4 2021	915,720	$201,090	$194.45	$176.36 - $224.49
Q3 2021	165,936	$30,098	$195.24	$180.02 - $204.88
Q2 2021	141,741	$28,577	$209.17	$185.33 - $222.78
Q1 2021	115,885	$24,902	$219.65	$204.62 - $242.99
Q4 2020	132,109	$31,221	$229.44	$202.57 - $280.99
Q3 2020	206,182	$56,105	$275.88	$253.97 - $306.08
Q2 2020	200,223	$58,125	$271.12	$222.39 - $299.21
Q1 2020	58,623	$13,948	$229.39	$197.47 - $249.85
Q4 2019	55,359	$12,120	$202.38	$165.23 - $225.66
Q3 2019	54,332	$9,204	$176.91	$165.27 - $188.44
Q2 2019	78,530	$14,400	$174.82	$163.68 - $191.71
Q1 2019	86,227	$15,861	$184.70	$160.95 - $195.81
Q4 2018	33,050	$5,476	$173.27	$151.80 - $194.92
Q3 2018	38,987	$7,514	$178.07	$164.70 - $193.78
Q2 2018	31,735	$5,393	$155.01	$144.07 - $172.00
Q1 2018	159,507	$25,996	$163.34	$146.21 - $178.15
Q4 2017	173,986	$26,073	$148.07	$136.50 - $158.04
Q3 2017	173,422	$26,367	$150.51	$125.50 - $167.86
Q2 2017	201,167	$25,924	$120.38	$107.24 - $137.26
Q1 2017	456,073	$49,871	$88.04	$73.34 - $111.88
Q4 2016	725,404	$53,440	$81.37	$71.46 - $97.93
Q3 2016	1,197,473	$104,429	$94.50	$83.50 - $103.73
Q2 2016	1,265,758	$108,879	$86.41	$75.92 - $96.49
Q1 2016	982,343	$78,085	$90.45	$75.90 - $124.96
Q4 2015	785,410	$98,826	$120.72	$101.49 - $134.71
Q3 2015	1,247,845	$129,949	$128.47	$97.45 - $143.45
Q2 2015	1,931,356	$238,482	$125.98	$113.68 - $137.50
Q1 2015	2,085,541	$246,029	$119.81	$103.75 - $136.33
Q4 2014	2,334,959	$277,391	$112.63	$96.43 - $124.35
Q3 2014	2,524,532	$283,529	$95.21	$84.41 - $116.88
Q2 2014	2,627,189	$248,740	$70.12	$59.79 - $98.80
Q1 2014	2,756,735	$194,955	$79.20	$67.49 - $87.77
Q4 2013	3,342,401	$248,339	$69.64	$58.06 - $78.38
Q3 2013	3,389,304	$256,976	$79.58	$73.43 - $89.96
Q2 2013	3,650,067	$291,529	$73.64	$51.28 - $87.47