VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

COUNTRY TRUST BANK's Holding History (CIK: 0001209324)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 100,593 Value ($000) $45,605 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 98,532 Value ($000) $38,589 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 90,136 Value ($000) $40,129 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 89,824 Value ($000) $43,548 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 83,602 Value ($000) $33,667 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 94,091 Value ($000) $43,760 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 94,341 Value ($000) $44,220 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 94,325 Value ($000) $39,429 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 102,184 Value ($000) $41,578 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 119,789 Value ($000) $41,655 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 133,266 Value ($000) $46,898 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 137,701 Value ($000) $43,385 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 147,423 Value ($000) $42,573 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 148,363 Value ($000) $42,957 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 130,611 Value ($000) $36,805 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 137,638 Value ($000) $35,919 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 179,668 Value ($000) $39,455 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 160,399 Value ($000) $29,095 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 94,768 Value ($000) $19,108 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 180 Value ($000) $39 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 180 Value ($000) $43 Avg Close $229.44 Range $202.57 - $280.99

Q4 2018

Shares 14 Value ($000) $2 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 8 Value ($000) $2 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 8 Value ($000) $1 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 38 Value ($000) $6 Avg Close $163.34 Range $146.21 - $178.15

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	100,593	$45,605	$431.03	$392.50 - $464.44
Q3 2025	98,532	$38,589	$417.92	$362.50 - $484.56
Q2 2025	90,136	$40,129	$460.83	$416.60 - $510.77
Q1 2025	89,824	$43,548	$466.00	$397.25 - $519.68
Q4 2024	83,602	$33,667	$463.53	$377.85 - $519.88
Q3 2024	94,091	$43,760	$480.37	$456.07 - $510.64
Q2 2024	94,341	$44,220	$434.05	$391.01 - $486.43
Q1 2024	94,325	$39,429	$422.74	$403.43 - $448.40
Q4 2023	102,184	$41,578	$369.42	$341.85 - $413.00
Q3 2023	119,789	$41,655	$349.73	$335.82 - $367.00
Q2 2023	133,266	$46,898	$336.94	$313.47 - $354.94
Q1 2023	137,701	$43,385	$299.93	$282.21 - $325.19
Q4 2022	147,423	$42,573	$304.77	$283.58 - $324.75
Q3 2022	148,363	$42,957	$287.72	$271.61 - $305.95
Q2 2022	130,611	$36,805	$267.66	$233.01 - $293.17
Q1 2022	137,638	$35,919	$237.33	$214.66 - $263.58
Q4 2021	179,668	$39,455	$194.45	$176.36 - $224.49
Q3 2021	160,399	$29,095	$195.24	$180.02 - $204.88
Q2 2021	94,768	$19,108	$209.17	$185.33 - $222.78
Q1 2021	180	$39	$219.65	$204.62 - $242.99
Q4 2020	180	$43	$229.44	$202.57 - $280.99
Q4 2018	14	$2	$173.27	$151.80 - $194.92
Q3 2018	8	$2	$178.07	$164.70 - $193.78
Q2 2018	8	$1	$155.01	$144.07 - $172.00
Q1 2018	38	$6	$163.34	$146.21 - $178.15