VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

NORDEA INVESTMENT MANAGEMENT AB's Holding History (CIK: 0001218210)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 447,169 Value ($000) $202,612 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 361,085 Value ($000) $140,119 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 24,512 Value ($000) $10,889 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 23,455 Value ($000) $11,368 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 342,429 Value ($000) $137,783 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 286,690 Value ($000) $133,024 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 353,235 Value ($000) $167,267 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 331,469 Value ($000) $139,147 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 321,331 Value ($000) $131,180 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 310,072 Value ($000) $109,406 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 288,938 Value ($000) $102,142 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 268,226 Value ($000) $84,502 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 299,360 Value ($000) $85,862 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 272,761 Value ($000) $79,643 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 250,238 Value ($000) $69,669 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 269,704 Value ($000) $69,554 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 266,994 Value ($000) $59,403 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 237,181 Value ($000) $43,653 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 212,617 Value ($000) $42,870 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 192,526 Value ($000) $41,279 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 139,025 Value ($000) $32,857 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 106,603 Value ($000) $28,952 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 179,992 Value ($000) $51,664 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 59,958 Value ($000) $13,904 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 61,519 Value ($000) $13,439 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 55,906 Value ($000) $9,404 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 54,990 Value ($000) $10,089 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 46,959 Value ($000) $8,638 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 13,840 Value ($000) $2,294 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 13,830 Value ($000) $2,666 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 17,520 Value ($000) $2,978 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 12,245 Value ($000) $1,996 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 12,311 Value ($000) $1,845 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 12,642 Value ($000) $1,922 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 12,466 Value ($000) $1,606 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 12,308 Value ($000) $1,346 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 10,085 Value ($000) $743 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 10,211 Value ($000) $891 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 9,947 Value ($000) $856 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 9,947 Value ($000) $791 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 9,947 Value ($000) $1,252 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 8,601 Value ($000) $896 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 8,601 Value ($000) $1,062 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 8,796 Value ($000) $1,038 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 8,796 Value ($000) $1,045 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 9,977 Value ($000) $1,121 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 19,711 Value ($000) $1,866 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 19,711 Value ($000) $1,394 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 18,835 Value ($000) $1,399 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 17,557 Value ($000) $1,331 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 14,148 Value ($000) $1,130 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	447,169	$202,612	$431.03	$392.50 - $464.44
Q3 2025	361,085	$140,119	$417.92	$362.50 - $484.56
Q2 2025	24,512	$10,889	$460.83	$416.60 - $510.77
Q1 2025	23,455	$11,368	$466.00	$397.25 - $519.68
Q4 2024	342,429	$137,783	$463.53	$377.85 - $519.88
Q3 2024	286,690	$133,024	$480.37	$456.07 - $510.64
Q2 2024	353,235	$167,267	$434.05	$391.01 - $486.43
Q1 2024	331,469	$139,147	$422.74	$403.43 - $448.40
Q4 2023	321,331	$131,180	$369.42	$341.85 - $413.00
Q3 2023	310,072	$109,406	$349.73	$335.82 - $367.00
Q2 2023	288,938	$102,142	$336.94	$313.47 - $354.94
Q1 2023	268,226	$84,502	$299.93	$282.21 - $325.19
Q4 2022	299,360	$85,862	$304.77	$283.58 - $324.75
Q3 2022	272,761	$79,643	$287.72	$271.61 - $305.95
Q2 2022	250,238	$69,669	$267.66	$233.01 - $293.17
Q1 2022	269,704	$69,554	$237.33	$214.66 - $263.58
Q4 2021	266,994	$59,403	$194.45	$176.36 - $224.49
Q3 2021	237,181	$43,653	$195.24	$180.02 - $204.88
Q2 2021	212,617	$42,870	$209.17	$185.33 - $222.78
Q1 2021	192,526	$41,279	$219.65	$204.62 - $242.99
Q4 2020	139,025	$32,857	$229.44	$202.57 - $280.99
Q3 2020	106,603	$28,952	$275.88	$253.97 - $306.08
Q2 2020	179,992	$51,664	$271.12	$222.39 - $299.21
Q1 2020	59,958	$13,904	$229.39	$197.47 - $249.85
Q4 2019	61,519	$13,439	$202.38	$165.23 - $225.66
Q3 2019	55,906	$9,404	$176.91	$165.27 - $188.44
Q2 2019	54,990	$10,089	$174.82	$163.68 - $191.71
Q1 2019	46,959	$8,638	$184.70	$160.95 - $195.81
Q4 2018	13,840	$2,294	$173.27	$151.80 - $194.92
Q3 2018	13,830	$2,666	$178.07	$164.70 - $193.78
Q2 2018	17,520	$2,978	$155.01	$144.07 - $172.00
Q1 2018	12,245	$1,996	$163.34	$146.21 - $178.15
Q4 2017	12,311	$1,845	$148.07	$136.50 - $158.04
Q3 2017	12,642	$1,922	$150.51	$125.50 - $167.86
Q2 2017	12,466	$1,606	$120.38	$107.24 - $137.26
Q1 2017	12,308	$1,346	$88.04	$73.34 - $111.88
Q4 2016	10,085	$743	$81.37	$71.46 - $97.93
Q3 2016	10,211	$891	$94.50	$83.50 - $103.73
Q2 2016	9,947	$856	$86.41	$75.92 - $96.49
Q1 2016	9,947	$791	$90.45	$75.90 - $124.96
Q4 2015	9,947	$1,252	$120.72	$101.49 - $134.71
Q3 2015	8,601	$896	$128.47	$97.45 - $143.45
Q2 2015	8,601	$1,062	$125.98	$113.68 - $137.50
Q1 2015	8,796	$1,038	$119.81	$103.75 - $136.33
Q4 2014	8,796	$1,045	$112.63	$96.43 - $124.35
Q3 2014	9,977	$1,121	$95.21	$84.41 - $116.88
Q2 2014	19,711	$1,866	$70.12	$59.79 - $98.80
Q1 2014	19,711	$1,394	$79.20	$67.49 - $87.77
Q4 2013	18,835	$1,399	$69.64	$58.06 - $78.38
Q3 2013	17,557	$1,331	$79.58	$73.43 - $89.96
Q2 2013	14,148	$1,130	$73.64	$51.28 - $87.47