VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

OPPENHEIMER ASSET MANAGEMENT INC.'s Holding History (CIK: 0001269119)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 16,720 Value ($000) $7,580 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 25,460 Value ($000) $9,971 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 21,488 Value ($000) $9,566 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 21,694 Value ($000) $10,518 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 20,528 Value ($000) $8,267 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 23,390 Value ($000) $10,878 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 24,368 Value ($000) $11,422 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 14,411 Value ($000) $6,024 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 16,472 Value ($000) $6,702 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 14,030 Value ($000) $4,879 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 14,108 Value ($000) $4,965 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 14,308 Value ($000) $4,508 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 15,226 Value ($000) $4,397 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 15,110 Value ($000) $4,374 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 13,454 Value ($000) $3,792 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 14,250 Value ($000) $3,719 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 14,711 Value ($000) $3,231 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 11,443 Value ($000) $2,077 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 28,564 Value ($000) $5,760 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 28,294 Value ($000) $6,081 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 27,900 Value ($000) $6,593 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 26,487 Value ($000) $7,208 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 26,165 Value ($000) $7,595 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 31,330 Value ($000) $7,454 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 33,888 Value ($000) $7,418 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 37,073 Value ($000) $6,281 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 48,505 Value ($000) $8,895 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 48,807 Value ($000) $8,979 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 52,612 Value ($000) $8,718 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 54,193 Value ($000) $10,445 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 51,949 Value ($000) $8,830 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 36,835 Value ($000) $6,004 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 25,745 Value ($000) $3,913 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 25,745 Value ($000) $3,913 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 14,463 Value ($000) $1,863 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 7,627 Value ($000) $834 Avg Close $88.04 Range $73.34 - $111.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	16,720	$7,580	$431.03	$392.50 - $464.44
Q3 2025	25,460	$9,971	$417.92	$362.50 - $484.56
Q2 2025	21,488	$9,566	$460.83	$416.60 - $510.77
Q1 2025	21,694	$10,518	$466.00	$397.25 - $519.68
Q4 2024	20,528	$8,267	$463.53	$377.85 - $519.88
Q3 2024	23,390	$10,878	$480.37	$456.07 - $510.64
Q2 2024	24,368	$11,422	$434.05	$391.01 - $486.43
Q1 2024	14,411	$6,024	$422.74	$403.43 - $448.40
Q4 2023	16,472	$6,702	$369.42	$341.85 - $413.00
Q3 2023	14,030	$4,879	$349.73	$335.82 - $367.00
Q2 2023	14,108	$4,965	$336.94	$313.47 - $354.94
Q1 2023	14,308	$4,508	$299.93	$282.21 - $325.19
Q4 2022	15,226	$4,397	$304.77	$283.58 - $324.75
Q3 2022	15,110	$4,374	$287.72	$271.61 - $305.95
Q2 2022	13,454	$3,792	$267.66	$233.01 - $293.17
Q1 2022	14,250	$3,719	$237.33	$214.66 - $263.58
Q4 2021	14,711	$3,231	$194.45	$176.36 - $224.49
Q3 2021	11,443	$2,077	$195.24	$180.02 - $204.88
Q2 2021	28,564	$5,760	$209.17	$185.33 - $222.78
Q1 2021	28,294	$6,081	$219.65	$204.62 - $242.99
Q4 2020	27,900	$6,593	$229.44	$202.57 - $280.99
Q3 2020	26,487	$7,208	$275.88	$253.97 - $306.08
Q2 2020	26,165	$7,595	$271.12	$222.39 - $299.21
Q1 2020	31,330	$7,454	$229.39	$197.47 - $249.85
Q4 2019	33,888	$7,418	$202.38	$165.23 - $225.66
Q3 2019	37,073	$6,281	$176.91	$165.27 - $188.44
Q2 2019	48,505	$8,895	$174.82	$163.68 - $191.71
Q1 2019	48,807	$8,979	$184.70	$160.95 - $195.81
Q4 2018	52,612	$8,718	$173.27	$151.80 - $194.92
Q3 2018	54,193	$10,445	$178.07	$164.70 - $193.78
Q2 2018	51,949	$8,830	$155.01	$144.07 - $172.00
Q1 2018	36,835	$6,004	$163.34	$146.21 - $178.15
Q4 2017	25,745	$3,913	$148.07	$136.50 - $158.04
Q3 2017	25,745	$3,913	$150.51	$125.50 - $167.86
Q2 2017	14,463	$1,863	$120.38	$107.24 - $137.26
Q1 2017	7,627	$834	$88.04	$73.34 - $111.88