VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Advisors Asset Management, Inc.'s Holding History (CIK: 0001297376)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 24,713 Value ($000) $11,204 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 25,926 Value ($000) $10,154 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 25,085 Value ($000) $11,168 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 27,744 Value ($000) $13,451 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 27,612 Value ($000) $11,119 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 26,467 Value ($000) $12,309 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 23,108 Value ($000) $10,831 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 21,384 Value ($000) $8,939 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 17,728 Value ($000) $7,213 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 17,476 Value ($000) $6,077 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 15,626 Value ($000) $5,499 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 13,495 Value ($000) $4,252 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 11,786 Value ($000) $3,404 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 12,199 Value ($000) $3,532 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 10,866 Value ($000) $3,062 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 15,866 Value ($000) $4,141 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 21,242 Value ($000) $4,665 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 25,700 Value ($000) $4,662 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 27,667 Value ($000) $5,578 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 30,759 Value ($000) $6,610 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 28,155 Value ($000) $6,654 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 24,871 Value ($000) $6,768 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 24,166 Value ($000) $7,016 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 19,824 Value ($000) $4,717 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 16,958 Value ($000) $3,713 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 15,485 Value ($000) $2,623 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 16,507 Value ($000) $3,027 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 20,119 Value ($000) $3,701 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 17,550 Value ($000) $2,908 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 14,092 Value ($000) $2,716 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 15,434 Value ($000) $2,623 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 12,740 Value ($000) $2,115 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 13,380 Value ($000) $2,005 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 13,231 Value ($000) $2,012 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 14,993 Value ($000) $1,932 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 15,843 Value ($000) $1,732 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 28,233 Value ($000) $2,080 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 28,622 Value ($000) $2,496 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 34,733 Value ($000) $2,988 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 36,369 Value ($000) $2,891 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 45,011 Value ($000) $5,664 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 46,928 Value ($000) $4,887 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 40,954 Value ($000) $5,057 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 37,211 Value ($000) $4,390 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 27,950 Value ($000) $3,320 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 23,044 Value ($000) $2,588 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 13,916 Value ($000) $1,318 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 6,248 Value ($000) $442 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 1,300 Value ($000) $97 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 1,200 Value ($000) $91 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 7,000 Value ($000) $559 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	24,713	$11,204	$431.03	$392.50 - $464.44
Q3 2025	25,926	$10,154	$417.92	$362.50 - $484.56
Q2 2025	25,085	$11,168	$460.83	$416.60 - $510.77
Q1 2025	27,744	$13,451	$466.00	$397.25 - $519.68
Q4 2024	27,612	$11,119	$463.53	$377.85 - $519.88
Q3 2024	26,467	$12,309	$480.37	$456.07 - $510.64
Q2 2024	23,108	$10,831	$434.05	$391.01 - $486.43
Q1 2024	21,384	$8,939	$422.74	$403.43 - $448.40
Q4 2023	17,728	$7,213	$369.42	$341.85 - $413.00
Q3 2023	17,476	$6,077	$349.73	$335.82 - $367.00
Q2 2023	15,626	$5,499	$336.94	$313.47 - $354.94
Q1 2023	13,495	$4,252	$299.93	$282.21 - $325.19
Q4 2022	11,786	$3,404	$304.77	$283.58 - $324.75
Q3 2022	12,199	$3,532	$287.72	$271.61 - $305.95
Q2 2022	10,866	$3,062	$267.66	$233.01 - $293.17
Q1 2022	15,866	$4,141	$237.33	$214.66 - $263.58
Q4 2021	21,242	$4,665	$194.45	$176.36 - $224.49
Q3 2021	25,700	$4,662	$195.24	$180.02 - $204.88
Q2 2021	27,667	$5,578	$209.17	$185.33 - $222.78
Q1 2021	30,759	$6,610	$219.65	$204.62 - $242.99
Q4 2020	28,155	$6,654	$229.44	$202.57 - $280.99
Q3 2020	24,871	$6,768	$275.88	$253.97 - $306.08
Q2 2020	24,166	$7,016	$271.12	$222.39 - $299.21
Q1 2020	19,824	$4,717	$229.39	$197.47 - $249.85
Q4 2019	16,958	$3,713	$202.38	$165.23 - $225.66
Q3 2019	15,485	$2,623	$176.91	$165.27 - $188.44
Q2 2019	16,507	$3,027	$174.82	$163.68 - $191.71
Q1 2019	20,119	$3,701	$184.70	$160.95 - $195.81
Q4 2018	17,550	$2,908	$173.27	$151.80 - $194.92
Q3 2018	14,092	$2,716	$178.07	$164.70 - $193.78
Q2 2018	15,434	$2,623	$155.01	$144.07 - $172.00
Q1 2018	12,740	$2,115	$163.34	$146.21 - $178.15
Q4 2017	13,380	$2,005	$148.07	$136.50 - $158.04
Q3 2017	13,231	$2,012	$150.51	$125.50 - $167.86
Q2 2017	14,993	$1,932	$120.38	$107.24 - $137.26
Q1 2017	15,843	$1,732	$88.04	$73.34 - $111.88
Q4 2016	28,233	$2,080	$81.37	$71.46 - $97.93
Q3 2016	28,622	$2,496	$94.50	$83.50 - $103.73
Q2 2016	34,733	$2,988	$86.41	$75.92 - $96.49
Q1 2016	36,369	$2,891	$90.45	$75.90 - $124.96
Q4 2015	45,011	$5,664	$120.72	$101.49 - $134.71
Q3 2015	46,928	$4,887	$128.47	$97.45 - $143.45
Q2 2015	40,954	$5,057	$125.98	$113.68 - $137.50
Q1 2015	37,211	$4,390	$119.81	$103.75 - $136.33
Q4 2014	27,950	$3,320	$112.63	$96.43 - $124.35
Q3 2014	23,044	$2,588	$95.21	$84.41 - $116.88
Q2 2014	13,916	$1,318	$70.12	$59.79 - $98.80
Q1 2014	6,248	$442	$79.20	$67.49 - $87.77
Q4 2013	1,300	$97	$69.64	$58.06 - $78.38
Q3 2013	1,200	$91	$79.58	$73.43 - $89.96
Q2 2013	7,000	$559	$73.64	$51.28 - $87.47