VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Coastline Trust Co's Holding History (CIK: 0001324279)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 597 Value ($000) $271 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 597 Value ($000) $234 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 3,742 Value ($000) $1,666 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 3,742 Value ($000) $1,814 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 3,517 Value ($000) $1,416 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 6,579 Value ($000) $3,060 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 5,819 Value ($000) $2,727 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 5,799 Value ($000) $2,424 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 1,015 Value ($000) $413 Avg Close $369.42 Range $341.85 - $413.00

Q3 2020

Shares 1,150 Value ($000) $313 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 1,550 Value ($000) $450 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 1,550 Value ($000) $369 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 1,550 Value ($000) $339 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 1,559 Value ($000) $264 Avg Close $176.91 Range $165.27 - $188.44

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	597	$271	$431.03	$392.50 - $464.44
Q3 2025	597	$234	$417.92	$362.50 - $484.56
Q2 2025	3,742	$1,666	$460.83	$416.60 - $510.77
Q1 2025	3,742	$1,814	$466.00	$397.25 - $519.68
Q4 2024	3,517	$1,416	$463.53	$377.85 - $519.88
Q3 2024	6,579	$3,060	$480.37	$456.07 - $510.64
Q2 2024	5,819	$2,727	$434.05	$391.01 - $486.43
Q1 2024	5,799	$2,424	$422.74	$403.43 - $448.40
Q4 2023	1,015	$413	$369.42	$341.85 - $413.00
Q3 2020	1,150	$313	$275.88	$253.97 - $306.08
Q2 2020	1,550	$450	$271.12	$222.39 - $299.21
Q1 2020	1,550	$369	$229.39	$197.47 - $249.85
Q4 2019	1,550	$339	$202.38	$165.23 - $225.66
Q3 2019	1,559	$264	$176.91	$165.27 - $188.44